Therapeutic strategies targeting FOXO transcription factors
FOXO proteins are transcription factors that are involved in numerous physiological
processes and in various pathological conditions, including cardiovascular disease, cancer …
processes and in various pathological conditions, including cardiovascular disease, cancer …
Cancer and the circadian clock
AA Shafi, KE Knudsen - Cancer research, 2019 - AACR
The circadian clock is a master regulator of mammalian physiology, regulating daily
oscillations of crucial biological processes and behaviors. Notably, circadian disruption has …
oscillations of crucial biological processes and behaviors. Notably, circadian disruption has …
An efficient method to isolate lemon derived extracellular vesicles for gastric cancer therapy
M Yang, X Liu, Q Luo, L Xu, F Chen - Journal of nanobiotechnology, 2020 - Springer
Background Plant-derived extracellular vesicles (PDEVs) have great potential for clinical
applications. Ultracentrifugation, considered the gold standard method for the preparation of …
applications. Ultracentrifugation, considered the gold standard method for the preparation of …
Extracellular vesicles from plants: current knowledge and open questions
The scientific interest in the beneficial properties of natural substances has been recognized
for decades, as well as the growing attention in extracellular vesicles (EVs) released by …
for decades, as well as the growing attention in extracellular vesicles (EVs) released by …
Targeting apoptosis pathways in cancer and perspectives with natural compounds from mother nature
FM Millimouno, J Dong, L Yang, J Li, X Li - Cancer prevention research, 2014 - AACR
Although the incidences are increasing day after day, scientists and researchers taken
individually or by research group are trying to fight against cancer by several ways and also …
individually or by research group are trying to fight against cancer by several ways and also …
A review of common cyanotoxins and their effects on fish
Global warming and human-induced eutrophication drive the occurrence of various
cyanotoxins in aquatic environments. These metabolites reveal diversified mechanisms of …
cyanotoxins in aquatic environments. These metabolites reveal diversified mechanisms of …
Why is longevity still a scientific mystery? Sirtuins—past, present and future
P Ziętara, M Dziewięcka, M Augustyniak - International Journal of …, 2022 - mdpi.com
The sirtuin system consists of seven highly conserved regulatory enzymes responsible for
metabolism, antioxidant protection, and cell cycle regulation. The great interest in sirtuins is …
metabolism, antioxidant protection, and cell cycle regulation. The great interest in sirtuins is …
Epigenome-associated phenotypic acclimatization to ocean acidification in a reef-building coral
There are increasing concerns that the current rate of climate change might outpace the
ability of reef-building corals to adapt to future conditions. Work on model systems has …
ability of reef-building corals to adapt to future conditions. Work on model systems has …
DNA demethylation pathways: additional players and regulators
M Bochtler, A Kolano, GL Xu - Bioessays, 2017 - Wiley Online Library
DNA demethylation can occur passively by “dilution” of methylation marks by DNA
replication, or actively and independently of DNA replication. Direct conversion of 5 …
replication, or actively and independently of DNA replication. Direct conversion of 5 …
Mechanisms of African swine fever virus pathogenesis and immune evasion inferred from gene expression changes in infected swine macrophages
JJ Zhu, P Ramanathan, EA Bishop, V O'Donnell… - PloS one, 2019 - journals.plos.org
African swine fever (ASF) is a swine disease caused by a large, structurally complex, double-
stranded DNA virus, African swine fever virus (ASFV). In domestic pigs, acute infection by …
stranded DNA virus, African swine fever virus (ASFV). In domestic pigs, acute infection by …