Recurrent wheezing is a common problem in young children: approximately 40% of children
wheeze in their first year of life. However, only 30% of preschoolers with recurrent wheezing …

This review addresses predictors of remission or persistence of wheezing and asthma from
early childhood through adulthood. Early childhood wheezing is common, but predicting …

Background While it is suggested that the prevalence of asthma in developed countries may
have stabilized, this is not clear in currently developing countries. Current available …

Rationale: Clinical and epidemiologic approaches have identified two distinct sets of
classifications for asthma and wheeze phenotypes. Objectives: To compare epidemiologic …

Background Attacks of wheezing induced by upper respiratory viral infections are common
in preschool children between the ages of 10 months and 6 years. A short course of oral …

Background Asthma phenotypes are currently not amenable to primary prevention or early
intervention because their natural history cannot be reliably predicted. Clinicians remain …

Background Wheeze is one of the most common symptoms of preschool children (age 1-5
years), yet we have little understanding of the burden in the United Kingdom. Objectives We …

BACKGROUND: Increased airway smooth muscle (ASM) is a feature of established asthma
in schoolchildren, but nothing is known about ASM in preschool wheezers. OBJECTIVE: We …

Background The inability to objectively diagnose childhood asthma before age five often
results in both under‐treatment and over‐treatment of asthma in preschool children …

Background Prediction of subsequent school-age asthma during the preschool years has
proven challenging. Objective To confirm in a post hoc analysis the predictive ability of the …