Identification of a cellular role of hemolysin co-regulatory protein (Hcp) in Vibrio alginolyticus modulating substrate metabolism and biofilm formation by cAMP-CRP

S Wu, Y Huang, M Wu, H Chen, B Wang… - International Journal of …, 2024 - Elsevier
Cyclic AMP (cAMP) and cAMP receptor protein (CRP) system controls catabolic enzyme
expression based on metabolite concentrations in bacteria. Hemolysin co-regulatory protein …

Predicting bacterial transcription factor binding sites through machine learning and structural characterization based on DNA duplex stability

A Borges Farias, G Sganzerla Martinez… - Briefings in …, 2024 - academic.oup.com
Transcriptional factors (TFs) in bacteria play a crucial role in gene regulation by binding to
specific DNA sequences, thereby assisting in the activation or repression of genes. Despite …

HemoFuse: multi-feature fusion based on multi-head cross-attention for identification of hemolytic peptides

Y Zhao, S Zhang, Y Liang - Scientific Reports, 2024 - nature.com
Hemolytic peptides are therapeutic peptides that damage red blood cells. However,
therapeutic peptides used in medical treatment must exhibit low toxicity to red blood cells to …

A Causal Regulation Modeling Algorithm for Temporal Events with Application to Escherichia coli's Aerobic to Anaerobic Transition

Y Chen, R Mao, J Xu, Y Huang, J Xu, S Cui… - International Journal of …, 2024 - mdpi.com
Time-series experiments are crucial for understanding the transient and dynamic nature of
biological phenomena. These experiments, leveraging advanced classification and …