Delivering on the promise of recombinant silk-inspired proteins for drug delivery

C Gonzalez-Obeso, EJ Hartzell, RA Scheel… - Advanced drug delivery …, 2023 - Elsevier
Effective drug delivery is essential for the success of a medical treatment. Polymeric drug
delivery systems (DDSs) are preferred over systemic administration of drugs due to their …

Silk: a promising biomaterial opening new vistas towards affordable healthcare solutions

A Bandyopadhyay, SK Chowdhury, S Dey… - Journal of the Indian …, 2019 - Springer
Substantial progress in biomaterial research over the years has culminated in revolutionary
technological advancements in the healthcare domain. This has triggered the quest for …

Self-assembly of RGD-functionalized recombinant spider silk protein into microspheres in physiological buffer and in the presence of hyaluronic acid

E Ornithopoulou, C Åstrand, L Gustafsson… - ACS Applied Bio …, 2023 - ACS Publications
Biomaterials made of self-assembling protein building blocks are widely explored for
biomedical applications, for example, as drug carriers, tissue engineering scaffolds, and …

A silk composite fiber reinforced by telechelic-type polyalanine and its strengthening mechanism

J Chen, K Tsuchiya, H Masunaga, AD Malay… - Polymer …, 2022 - pubs.rsc.org
Antiparallel β-sheets play a key role in determining the physical properties of fibroins, eg,
degradation and mechanical properties, and are typically formed by poly (A) motifs from …

Spider silk-inspired tough materials: Multi-pathway synthesis, advanced processing, and functional applications

Y Su, S Shi, C Wang, Z Wang, P Li, S Zhang, B Fei… - Nano Today, 2024 - Elsevier
Tough materials play an important role in human society, from daily life, and industry to
military. However, the contradiction between strength and ductility limits the development of …

Artificial silk fibers as biomaterials and their applications in biomedicine

J Chen, K Numata - Silk-Based Biomaterials for Tissue Engineering …, 2024 - Elsevier
In recent decades, scientists have been committed to scaling up artificial silk fibers with
similar mechanical properties to natural spider silks. It remains challenging to achieve this …

Bioinspired polypeptide as building blocks for multifunctional material design

N Kong, F Wan, W Dai, Y Lu, P Cheng, J Dai, Y Li… - Applied Materials …, 2020 - Elsevier
The exceptional mechanical properties of spider silks from their extraordinary natural design
make them outstanding biomaterial candidates. Herein, inspired by the outer egg sac silk …

Accelerated Reversible Conversion of Li2S2 to Li2S by Spidroin Regulated Li+ Flux for High‐performance Li‐Sulfur Batteries

A Coskun, M Liu, Z Wu, S Liu, T Guo, P Chen… - Angewandte Chemie … - Wiley Online Library
Regulating the transformation of sulfur species is the key to improving the electrochemical
performance of lithium‐sulfur (Li‐S) batteries, in particular, to accelerate the reversible …

Facile fabrication of microspheres and microcapsules from a recombinant spider eggcase silk protein for drug delivery

J Chen, H Venkatesan, J Hu - AATCC Journal of Research, 2019 - journals.sagepub.com
Spider silk is renowned for its exceptional mechanical properties, and compatibility and
biodegradability for various functional applications, such as drug delivery. By a facile HFIP …