Delivering on the promise of recombinant silk-inspired proteins for drug delivery
C Gonzalez-Obeso, EJ Hartzell, RA Scheel… - Advanced drug delivery …, 2023 - Elsevier
Effective drug delivery is essential for the success of a medical treatment. Polymeric drug
delivery systems (DDSs) are preferred over systemic administration of drugs due to their …
delivery systems (DDSs) are preferred over systemic administration of drugs due to their …
Silk: a promising biomaterial opening new vistas towards affordable healthcare solutions
Substantial progress in biomaterial research over the years has culminated in revolutionary
technological advancements in the healthcare domain. This has triggered the quest for …
technological advancements in the healthcare domain. This has triggered the quest for …
Self-assembly of RGD-functionalized recombinant spider silk protein into microspheres in physiological buffer and in the presence of hyaluronic acid
E Ornithopoulou, C Åstrand, L Gustafsson… - ACS Applied Bio …, 2023 - ACS Publications
Biomaterials made of self-assembling protein building blocks are widely explored for
biomedical applications, for example, as drug carriers, tissue engineering scaffolds, and …
biomedical applications, for example, as drug carriers, tissue engineering scaffolds, and …
A silk composite fiber reinforced by telechelic-type polyalanine and its strengthening mechanism
J Chen, K Tsuchiya, H Masunaga, AD Malay… - Polymer …, 2022 - pubs.rsc.org
Antiparallel β-sheets play a key role in determining the physical properties of fibroins, eg,
degradation and mechanical properties, and are typically formed by poly (A) motifs from …
degradation and mechanical properties, and are typically formed by poly (A) motifs from …
Spider silk-inspired tough materials: Multi-pathway synthesis, advanced processing, and functional applications
Tough materials play an important role in human society, from daily life, and industry to
military. However, the contradiction between strength and ductility limits the development of …
military. However, the contradiction between strength and ductility limits the development of …
Artificial silk fibers as biomaterials and their applications in biomedicine
J Chen, K Numata - Silk-Based Biomaterials for Tissue Engineering …, 2024 - Elsevier
In recent decades, scientists have been committed to scaling up artificial silk fibers with
similar mechanical properties to natural spider silks. It remains challenging to achieve this …
similar mechanical properties to natural spider silks. It remains challenging to achieve this …
Bioinspired polypeptide as building blocks for multifunctional material design
N Kong, F Wan, W Dai, Y Lu, P Cheng, J Dai, Y Li… - Applied Materials …, 2020 - Elsevier
The exceptional mechanical properties of spider silks from their extraordinary natural design
make them outstanding biomaterial candidates. Herein, inspired by the outer egg sac silk …
make them outstanding biomaterial candidates. Herein, inspired by the outer egg sac silk …
Accelerated Reversible Conversion of Li2S2 to Li2S by Spidroin Regulated Li+ Flux for High‐performance Li‐Sulfur Batteries
Regulating the transformation of sulfur species is the key to improving the electrochemical
performance of lithium‐sulfur (Li‐S) batteries, in particular, to accelerate the reversible …
performance of lithium‐sulfur (Li‐S) batteries, in particular, to accelerate the reversible …
Facile fabrication of microspheres and microcapsules from a recombinant spider eggcase silk protein for drug delivery
J Chen, H Venkatesan, J Hu - AATCC Journal of Research, 2019 - journals.sagepub.com
Spider silk is renowned for its exceptional mechanical properties, and compatibility and
biodegradability for various functional applications, such as drug delivery. By a facile HFIP …
biodegradability for various functional applications, such as drug delivery. By a facile HFIP …