Cardiovascular magnetic resonance (CMR) is established in clinical practice for the
diagnosis and management of diseases of the cardiovascular system. However, current …

The contrast‐enhanced magnetic resonance imaging (MRI) signal is rarely a direct measure
of contrast concentration; rather it depends on the effect that the contrast agent has on the …

Background Quantification of myocardial blood flow requires knowledge of the amount of
contrast agent in the myocardial tissue and the arterial input function (AIF) driving the …

Background—Contrast MRI enhancement patterns in several pathophysiologies resulting
from ischemic myocardial injury are controversial or have not been investigated. We …

Background In cardiac syndrome X (a syndrome characterized by typical angina, abnormal
exercise-test results, and normal coronary arteries), conventional investigations have not …

Background—With MRI, an index of myocardial perfusion reserve (MPRI) can be
determined. We assessed the value of this technique for the noninvasive detection of …

The myocardial perfusion reserve, defined as the ratio of hyperemic and basal myocardial
blood flow, is a useful indicator of the functional significance of a coronary artery lesion …

Background Myocardial reperfusion is pivotal to the prognosis of patients with acute
myocardial infarction. In these patients, coronary flow is generally assessed by angiography …

Background Contrast-enhanced fast magnetic resonance (MR) images of acute, reperfused
human infarcts demonstrate regions of hypoenhancement and hyperenhancement. The …

The image intensity in many contrast agent perfusion studies is designed to be a function of
bulk tissue T1, which is, in turn, a function of the compartmental (vascular, interstitial, and …