Cancer is a daunting global problem confronting the world's population. The most frequent
therapeutic approaches include surgery, chemotherapy, radiotherapy, and more recently …

Tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) is a member of the
TNF superfamily that can lead to the induction of apoptosis in tumor or infected cells …

Although mesenchymal stem cells (MSC s) transplantation into the IVD (intervertebral disc)
may be beneficial in inhibiting apoptosis of nucleus pulposus cells (NPC s) and alleviating …

The use of reactive oxygen species (ROS) generators based on single‐atom catalysts
(SACs) has been an emerging strategy for mediating tumor therapy, however, the current …

Deregulated NF-κB signalling is implicated in the pathogenesis of numerous human
inflammatory disorders and malignancies. Consequently, the NF-κB pathway has attracted …

Drug resistance is a major problem in the treatment of cancer patients. Resistance can
develop after prolonged cycles of chemotherapy or can be present intrinsically in the patient …

The linear ubiquitin chain assembly complex (LUBAC) is the only known E3 ubiquitin ligase
which catalyses the generation of linear ubiquitin linkages de novo. LUBAC is a crucial …

Cancer cells utilise several mechanisms to increase their survival and progression as well
as their resistance to anticancer therapy: deregulation of growth regulatory pathways by …

Lung cancer is a leading cause of cancer death, and late diagnosis is one of the most
important reasons for the high mortality rate. microRNAs (miRNAs) are key players in gene …

Lung cancer is the most common cancer worldwide. Up to 85% of lung cancer cases are
diagnosed as non-small cell lung cancer (NSCLC). The effectiveness of NSCLC treatment is …