The intermolecular transformation of simple substrates into highly functionalized scaffolds
with multiple stereogenic centers is an attractive strategy in modern organic synthesis …

Synthesis of complex organic molecules from simple, cheap, and readily available starting
materials is one of the most challenging and desirable factors in organic synthesis. In the …

An efficient redox-neutral method has been developed for α-Csp3–H functionalization of
secondary cyclic amines via concurrent N-arylation/formal cross dehydrogenation coupling …

Unlike phosphonium ylides used extensively for C═ C bond formation, herein we disclose
the direct use of phosphonium salts for site-selective alkylation to p-quinols via a 5 …

A scalable total synthesis of a potent poly (ADP-ribose) polymerase (PARP) enzyme
inhibitor, Olaparib (Lynparza), approved by US FDA and EMA for ovarian cancer, is …

A catalyst-controlled divergent synthesis of bridged [3.3. 1] bis (indolyl)-oxanes and cis-[6.7]
fused bis (indolyl) oxepanes via diastereoselective desymmetrization of bis (indolyl) …

An efficient method for the stereoselective synthesis of “all center substituted” polycyclic
pyrazoles from alkynyl cyclohexa-2, 5-dienones and nonstabilized diazoalkanes via …

An anion-relay double aza-Michael–Michael addition strategy has been reported for the
synthesis of intricate scaffolds from enone-tethered cyclohexadienones and primary amines …

A catalytic [3+ 2]-cycloaddition/Friedel–Crafts alkylative desymmetrization strategy has been
developed for the stereoselective construction of linear and bridged polycyclic pyrroles from …

The electrochemical oxidative dearomatizing methoxylation of phenols and naphthols was
developed. It provides an alternative route for the preparation of methoxycyclohexadienones …