Sex differences in systemic inflammation and immune function in diet‐induced obesity rodent models: A systematic review

JR Braga Tibaes, MI Barreto Silva, B Wollin… - Obesity …, 2024 - Wiley Online Library
Understanding sex differences in immunological responses in the context of obesity is
important to improve health outcomes. This systematic review aimed to investigate sex …

Obesity Alters POMC and Kisspeptin Neuron Cross Talk Leading to Reduced Luteinizing Hormone in Male Mice

PA Villa, RE Ruggiero-Ruff, BB Jamieson… - Journal of …, 2024 - jneurosci.org
Obesity is associated with hypogonadism in males, characterized by low testosterone and
sperm number. Previous studies determined that these stem from dysregulation of …

Key questions and gaps in understanding adipose tissue macrophages and early-life metabolic programming

KB Hill, GP Mullen, PR Nagareddy… - American Journal …, 2024 - journals.physiology.org
The global obesity epidemic, with its associated comorbidities and increased risk of early
mortality, underscores the urgent need for enhancing our understanding of the origins of this …

The regulatory role of eosinophils in adipose tissue depends on autophagy

A Hosseini, N Germic, N Markov, D Stojkov… - Frontiers in …, 2024 - frontiersin.org
Introduction Obesity is a metabolic condition that elevates the risk of all-cause mortality.
Brown and beige adipose tissues, known for their thermogenic properties, offer potential …

ABHD6 suppression promotes anti-inflammatory polarization of adipose tissue macrophages via 2-monoacylglycerol/PPAR signaling in obese mice

P Poursharifi, C Schmitt, I Chenier, YH Leung… - Molecular …, 2023 - Elsevier
Objective Pro-inflammatory polarization of adipose tissue macrophages (ATMs) plays a
critical role in the pathogenesis of obesity-associated chronic inflammation. However, little is …

Single-Cell Transcriptomics Identifies Pituitary Gland Changes in Diet-Induced Obesity in Male Mice

RE Ruggiero-Ruff, BH Le, PA Villa, NM Lainez… - …, 2024 - academic.oup.com
Obesity is a chronic disease with increasing prevalence worldwide. Obesity leads to an
increased risk of heart disease, stroke, and diabetes, as well as endocrine alterations …

Effects of oral copaiba-oil supplementation on visceral white adipose tissue content and histology of hypothalamic obese and non-obese male and female Wistar rats

H de França Kailer, E Stein, MH Forlin… - Medical Research …, 2024 - esmed.org
Background. Obesity involves the excessive expansion of white adipose tissue, typically
associated with adipocyte hypertrophy and inflammation, especially in visceral depots, a …

[图书][B] Immune cell-derived adipokines: role in white adipose tissue function and link to metabolic health

K Hofwimmer - 2024 - search.proquest.com
The white adipose tissue (WAT) is home to a vast array of immune cells that controllocal
homeostasis and metabolism by engaging in intricate crosstalk with adipocytesand their …