An overview of the role of neutrophils in innate immunity, inflammation and host-biomaterial integration
Despite considerable recent progress in defining neutrophil functions and behaviors in
tissue repair, much remains to be determined with regards to its overall role in the tissue …
tissue repair, much remains to be determined with regards to its overall role in the tissue …
Foreign body reaction to biomaterials
JM Anderson, A Rodriguez, DT Chang - Seminars in immunology, 2008 - Elsevier
The foreign body reaction composed of macrophages and foreign body giant cells is the end-
stage response of the inflammatory and wound healing responses following implantation of …
stage response of the inflammatory and wound healing responses following implantation of …
Porous implants modulate healing and induce shifts in local macrophage polarization in the foreign body reaction
EM Sussman, MC Halpin, J Muster, RT Moon… - Annals of biomedical …, 2014 - Springer
The foreign body reaction (FBR) to implanted materials is of critical importance when
medical devices require biological integration and vascularization to support their proper …
medical devices require biological integration and vascularization to support their proper …
Proangiogenic scaffolds as functional templates for cardiac tissue engineering
LR Madden, DJ Mortisen… - Proceedings of the …, 2010 - National Acad Sciences
We demonstrate here a cardiac tissue-engineering strategy addressing multicellular
organization, integration into host myocardium, and directional cues to reconstruct the …
organization, integration into host myocardium, and directional cues to reconstruct the …
Surface chemistry influences implant biocompatibility
Implantable medical devices are increasingly important in the practice of modern medicine.
Unfortunately, almost all medical devices suffer to a different extent from adverse reactions …
Unfortunately, almost all medical devices suffer to a different extent from adverse reactions …
Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans
L Chung, DR Maestas Jr, A Lebid, A Mageau… - Science translational …, 2020 - science.org
Medical devices and implants made of synthetic materials can induce an immune-mediated
process when implanted in the body called the foreign body response, which results in …
process when implanted in the body called the foreign body response, which results in …
Biosensors for real-time in vivo measurements
GS Wilson, R Gifford - Biosensors and Bioelectronics, 2005 - Elsevier
The current status of sensors capable of continuous measurement of analytes in biological
media is reviewed. This review containing 173 references deals with devices whose use in …
media is reviewed. This review containing 173 references deals with devices whose use in …
Characterization of topographical effects on macrophage behavior in a foreign body response model
S Chen, JA Jones, Y Xu, HY Low, JM Anderson… - Biomaterials, 2010 - Elsevier
Current strategies to limit macrophage adhesion, fusion and fibrous capsule formation in the
foreign body response have focused on modulating material surface properties. We …
foreign body response have focused on modulating material surface properties. We …
[图书][B] Principles of regenerative medicine
Principles of Regenerative Medicine, Third Edition, details the technologies and advances
applied in recent years to strategies for healing and generating tissue. Contributions from a …
applied in recent years to strategies for healing and generating tissue. Contributions from a …
Expanded applications, shifting paradigms and an improved understanding of host–biomaterial interactions
BN Brown, SF Badylak - Acta biomaterialia, 2013 - Elsevier
The conventional approach to biomaterial design and development typically focuses upon
the mechanical and material properties with long-term objectives that include an inert host …
the mechanical and material properties with long-term objectives that include an inert host …