In this paper, we report on the antimicrobial activity assessment of 49 compounds previously
synthesized as derivatives of alanine or phenylalanine that incorporate a 4-(4-X …

Some gene polymorphisms have been previously associated individually with tacrolimus
efficacy and toxicity, but no long-term study to determine the role of pharmacogene variants …

Lack of equitable representation of global genetic diversity has hampered the
implementation of genomic medicine in under-represented populations, including those on …

Biological therapies (BTs) indicated for psoriasis are highly effective; however, not all
patients obtain good results, and loss of effectiveness is the main reason for switching …

Dermatologic diseases are the fourth most frequent nonfatal common illness, yet they have a
psychological, economical, and professional burden that is comparable to or larger than …

Rheumatoid arthritis (RA) is characterized by persistent joint inflammation, a defining feature
of this chronic inflammatory condition. Considerable advancements have been made in the …

La psoriasis es una enfermedad cutánea autoinmune con una prevalencia entre el 2-4%.
Se caracteriza por el desarrollo de lesiones en forma de placas eritematosas con escamas …

A farmacogenômica é a ciência que estuda a interação entre genes e medicamentos,
buscando informações sobre o perfil de metabolização do paciente para um determinado …