Long COVID and the cardiovascular system—elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: a joint …

M Gyöngyösi, P Alcaide, FW Asselbergs… - Cardiovascular …, 2023 - academic.oup.com
Long COVID has become a world-wide, non-communicable epidemic, caused by long-
lasting multiorgan symptoms that endure for weeks or months after SARS-CoV-2 infection …

[HTML][HTML] Endotheliopathy in acute COVID-19 and long COVID

AG Vassiliou, CS Vrettou, C Keskinidou… - International Journal of …, 2023 - mdpi.com
The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …

[HTML][HTML] Soluble angiotensin converting enzyme 2 (ACE2) is upregulated and soluble endothelial nitric oxide synthase (eNOS) is downregulated in COVID-19-induced …

AG Vassiliou, A Zacharis, C Keskinidou, E Jahaj… - Pharmaceuticals, 2021 - mdpi.com
A damaged endothelium is an underlying condition of the many complications of COVID-19
patients. The increased mortality risk associated with diseases that have underlying …

[HTML][HTML] Angiotensin-Converting Enzyme (ACE) level, but not ACE gene polymorphism, is associated with prognosis of COVID-19 infection: Implications for diabetes …

O Elbasan, F Bayram, CD Yazan, T Apaydın… - PloS one, 2023 - journals.plos.org
Background The renin-angiotensin-aldosterone system was shown to be activated in severe
COVID-19 infection. We aimed to investigate the relationship between angiotensin …

Cardiovascular disease as part of Long COVID: a systematic review

V Tsampasian, M Bäck, M Bernardi… - European journal of …, 2024 - academic.oup.com
Aims Long COVID syndrome has had a major impact on million patients' lives worldwide.
The cardiovascular system is an important aspect of this multifaceted disease that may …

[HTML][HTML] Association of ACE1 I/D polymorphism and susceptibility to COVID-19 in Egyptian children and adolescents

NF Boraey, MA Bebars, AA Wahba… - Pediatric …, 2024 - nature.com
Background Given the sparse data on the renin-angiotensin system (RAS) and its biological
effector molecules ACE1 and ACE2 in pediatric COVID-19 cases, we investigated whether …

The prognostic importance of the angiotensin II/angiotensin-(1–7) ratio in patients with SARS-CoV-2 infection

LM Amezcua-Guerra, L Del Valle… - Therapeutic …, 2022 - journals.sagepub.com
Background: Information about angiotensin II (Ang II), angiotensin-converting enzyme 2
(ACE2), and Ang-(1–7) levels in patients with COVID-19 is scarce. Objective: To …

[HTML][HTML] The effect of influenza vaccine on severity of COVID-19 infection: An original study from Iran

S Kalantari, A Sadeghzadeh-Bazargan… - Medical Journal of the …, 2021 - ncbi.nlm.nih.gov
Background: The COVID-19 infection is a novel virus that mainly targets the respiratory
system via specific receptors without any coronavirus-targeted therapies. Many efforts have …

[HTML][HTML] Exploration of multifaceted molecular mechanism of angiotensin-converting enzyme 2 (ACE2) in pathogenesis of various diseases

AD Kunvariya, SA Dave, ZJ Modi, PK Patel, SR Sagar - Heliyon, 2023 - cell.com
Abstract Angiotensin converting enzyme 2 (ACE2) is a homolog of ACE (a transmembrane
bound dipeptidyl peptidase enzyme). ACE2 converts angiotensinogen to the heptapeptide …

[HTML][HTML] The Renin–Angiotensin System (RAS) in COVID-19 Disease: Where We Are 3 Years after the Beginning of the Pandemic

M Prato, N Tiberti, C Mazzi, F Gobbi, C Piubelli… - Microorganisms, 2024 - mdpi.com
The RAS is a hormonal system playing a pivotal role in the control of blood pressure and
electrolyte homeostasis, the alteration of which is associated with different pathologies …