Micron-scale magnetic resonance imaging based on low temperatures and dynamic nuclear polarization

R Tycko - Progress in Nuclear Magnetic Resonance …, 2023 - Elsevier
Extension of magnetic resonance imaging (MRI) techniques to the single micron scale has
been the goal of research in multiple laboratories over several decades. It has proven …

[HTML][HTML] Organization of descending neurons in Drosophila melanogaster

CT Hsu, V Bhandawat - Scientific reports, 2016 - nature.com
Neural processing in the brain controls behavior through descending neurons (DNs)-
neurons which carry signals from the brain to the spinal cord (or thoracic ganglia in insects) …

Probing the brain with molecular fMRI

S Ghosh, P Harvey, JC Simon, A Jasanoff - Current opinion in neurobiology, 2018 - Elsevier
Highlights•Molecular fMRI combines noninvasive imaging with target-sensitive molecular
probes.•Ca 2+-sensitive probes and fast fMRI methods could emulate optical calcium …

A simple setup for episcopic microtomy and a digital image processing workflow to acquire high-quality volume data and 3D surface models of small vertebrates

K Engelkes, F Friedrich, JU Hammel, A Haas - Zoomorphology, 2018 - Springer
The use of volume data and digital three-dimensional (3D) surface models in biology has
increased quickly and steadily. Various methods are available to acquire 3D data, among …

An optimized workflow for microCT imaging of formalin‐fixed and paraffin‐embedded (FFPE) early equine embryos

S Handschuh, CTC Okada, I Walter… - Anatomia, histologia …, 2022 - Wiley Online Library
Here, we describe a workflow for high‐detail microCT imaging of formalin‐fixed and paraffin‐
embedded (FFPE) equine embryos recovered on Day 34 of pregnancy (E34), a period just …

Low-temperature magnetic resonance imaging with 2.8 μm isotropic resolution

HY Chen, R Tycko - Journal of Magnetic Resonance, 2018 - Elsevier
We demonstrate the feasibility of high-resolution 1 H magnetic resonance imaging (MRI) at
low temperatures by obtaining an MRI image of 20 μm diameter glass beads in …

Micron-scale magnetic resonance imaging of both liquids and solids

E Moore, R Tycko - Journal of Magnetic Resonance, 2015 - Elsevier
We describe and demonstrate a novel apparatus for magnetic resonance imaging (MRI),
suitable for imaging of both liquid and solid samples with micron-scale isotropic resolution …

3D X-ray histology for the investigation of temporal lobe epilepsy in a mouse model

G Rodgers, C Bikis, P Janz, C Tanner… - Microscopy and …, 2023 - academic.oup.com
The most common form of epilepsy among adults is mesial temporal lobe epilepsy (mTLE),
with seizures often originating in the hippocampus due to abnormal electrical activity. The …

LYNSU: automated 3D neuropil segmentation of fluorescent images for Drosophila brains

KY Hsu, CT Shih, NY Chen, CC Lo - Frontiers in Neuroinformatics, 2024 - frontiersin.org
The brain atlas, which provides information about the distribution of genes, proteins,
neurons, or anatomical regions, plays a crucial role in contemporary neuroscience research …

Sleep homeostasis and general anesthesia: are fruit flies well rested after emergence from propofol?

B Gardner, E Strus, QC Meng, T Coradetti… - …, 2016 - pubs.asahq.org
Background Shared neurophysiologic features between sleep and anesthetic-induced
hypnosis indicate a potential overlap in neuronal circuitry underlying both states. Previous …