Centuries of genome instability and evolution in soft-shell clam, Mya arenaria, bivalve transmissible neoplasia
SFM Hart, MA Yonemitsu, RM Giersch, FES Garrett… - Nature Cancer, 2023 - nature.com
Transmissible cancers are infectious parasitic clones that metastasize to new hosts, living
past the death of the founder animal in which the cancer initiated. We investigated the …
past the death of the founder animal in which the cancer initiated. We investigated the …
Photosymbiosis shaped animal genome architecture and gene evolution as revealed in giant clams
Symbioses are major drivers of organismal diversification and phenotypic innovation.
However, how long-term symbioses shape whole genome evolution in metazoans is still …
However, how long-term symbioses shape whole genome evolution in metazoans is still …
A common garden experiment supports a genetic component underlying the increased resilience of common cockle (Cerastoderma edule) to the parasite Marteilia …
A Villalba, RM Coimbra, M Pampín… - Evolutionary …, 2023 - Wiley Online Library
The common cockle is a valuable bivalve species inhabiting the Atlantic European coasts.
The parasite Marteilia cochillia has devastated cockle beds in the southern Galician (NW …
The parasite Marteilia cochillia has devastated cockle beds in the southern Galician (NW …
Transmissible cancers, the genomes that do not melt down
Evolutionary theory predicts that accumulation of deleterious mutations in asexually
reproducing organisms should lead to genomic decay. Clonally reproducing cell lines, ie …
reproducing organisms should lead to genomic decay. Clonally reproducing cell lines, ie …
Unravelling epigenetic mechanisms in Cerastoderma edule genome: a comparison of healthy and neoplastic cockles
A Viña-Feás, J Temes-Rodríguez… - Molecular Genetics and …, 2024 - Springer
Cancer is a multifaceted genetic disease characterized by the acquisition of several
essential hallmarks. Notably, certain cancers exhibit horizontal transmissibility, observed …
essential hallmarks. Notably, certain cancers exhibit horizontal transmissibility, observed …
Multiple lineages of transmissible neoplasia in the basket cockle (C. nuttallii) with repeated horizontal transfer of mitochondrial DNA
Transmissible cancers are clonal lineages of neoplastic cells able to infect multiple hosts,
spreading through populations in the environment as an infectious disease. Transmissible …
spreading through populations in the environment as an infectious disease. Transmissible …
[HTML][HTML] Novel PCR assay for the identification of two transmissible cancers in Cerastoderma edule
M Santamarina, AL Bruzos, A Pequeño-Valtierra… - Journal of Invertebrate …, 2024 - Elsevier
Transmissible cancers are a rare phenomenon in which cancer cells are passed between
individuals, leading to the development of neoplasia in the host organism. Transmissible …
individuals, leading to the development of neoplasia in the host organism. Transmissible …
Horizontal transfer of nuclear DNA in transmissible cancer
Although somatic cell genomes are usually entirely clonally inherited, nuclear DNA
exchange between cells of an organism can occur sporadically by cell fusion, phagocytosis …
exchange between cells of an organism can occur sporadically by cell fusion, phagocytosis …
[HTML][HTML] Gene expression in soft-shell clam (Mya arenaria) transmissible cancer reveals survival mechanisms during host infection and seawater transfer
SFM Hart, FES Garrett, JS Kerr, MJ Metzger - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Transmissible cancers are unique instances in which cancer cells escape their original host
and spread through a population as a clonal lineage, documented in Tasmanian Devils …
and spread through a population as a clonal lineage, documented in Tasmanian Devils …
Long-read sequencing reveals extensive size variation and suggests evolutionary patterns of expansion in bivalve mitogenomes
Bilaterian mitochondrial genomes are generally of conserved size and gene content,
typically ranging from 14 to 20 kb and coding 37 genes. However, the major exception to this …
typically ranging from 14 to 20 kb and coding 37 genes. However, the major exception to this …