Genetic predisposition in type 2 diabetes: a promising approach toward a personalized management of diabetes
MM Sirdah, NS Reading - Clinical Genetics, 2020 - Wiley Online Library
Diabetes mellitus, also known simply as diabetes, has been described as a chronic and
complex endocrine metabolic disorder that is a leading cause of death across the globe. It is …
complex endocrine metabolic disorder that is a leading cause of death across the globe. It is …
Genetic Variants in the Fat Mass and Obesity‐Associated Gene and Risk of Obesity/Overweight in Children and Adolescents: A Systematic Review and Meta‐Analysis
M Eghbali, A Mottaghi, S Taghizadeh… - Endocrinology …, 2024 - Wiley Online Library
Objective The variations in the single‐nucleotide polymorphisms (SNPs) of the fat mass and
obesity (FTO)‐associated gene have been linked to being overweight or obese in children …
obesity (FTO)‐associated gene have been linked to being overweight or obese in children …
Association of an intronic SNP rs9939609 in FTO gene with type 2 diabetes mellitus among Bangladeshi population: A case–control study combined with updated …
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder, caused by both genetic
and environmental variables. The rs9939609 variant with a T> A mutation of the Fat mass …
and environmental variables. The rs9939609 variant with a T> A mutation of the Fat mass …
FTO gene variants (rs9939609, rs8050136 and rs17817449) and type 2 diabetes mellitus risk: A Meta-Analysis
MA Ikhanjal, MA Elouarid, C Zouine, K Errafii, H Ghazal… - Gene, 2023 - Elsevier
Background and aims There is tremendous increase in type 2 diabetes mellitus (T2DM)
worldwide. The impact of FTO gene polymorphisms on the risk of T2DM is not yet clear …
worldwide. The impact of FTO gene polymorphisms on the risk of T2DM is not yet clear …
Risk of type 2 diabetes and KCNJ11 gene polymorphisms: a nested case–control study and meta-analysis
M Moazzam-Jazi, L Najd-Hassan-Bonab… - Scientific Reports, 2022 - nature.com
Due to the central role in insulin secretion, the potassium inwardly-rectifying channel
subfamily J member 11 (KCNJ11) gene is one of the essential genes for type 2 diabetes …
subfamily J member 11 (KCNJ11) gene is one of the essential genes for type 2 diabetes …
Association analysis of FTO gene polymorphisms rs9939609 and obesity risk among the adults: A systematic review and meta-analysis
AH Abd Ali, TP Shkurat, AH Abbas - Meta Gene, 2021 - Elsevier
Background Obesity typically results from a variety of causes and factors which contribute,
genetics included, and style of living choices, and described as excessive body fat …
genetics included, and style of living choices, and described as excessive body fat …
Evaluation of interleukin-9 serum level and gene polymorphism in a sample of Iraqi type 2 diabetic mellitus patients
H Mohammed, DF Salloom - Meta Gene, 2021 - Elsevier
Background Diabetic mellitus (DM) is a collection of metabolic disorder identified by
hyperglycemia. The heterogeneous etiology includes defects either in insulin secretion, or in …
hyperglycemia. The heterogeneous etiology includes defects either in insulin secretion, or in …
Association between type 2 diabetes mellitus & TCF7L2 gene variants in the Emirati population: Genetics of diabetes in the United Arab Emirates
SM Khan, N El Karte… - American Journal of …, 2021 - Wiley Online Library
Objective Type 2 diabetes mellitus (T2DM) has a multifactorial etiology involving a complex
interplay between genes and the environment. The prevalence of T2DM among the …
interplay between genes and the environment. The prevalence of T2DM among the …
Genetic screening for pathogenic variants in type 2 diabetes of the Arab Gulf population: A systematic review and meta-analysis
Abstract Objective The Arab Gulf is highly vulnerable to T2DM and its serious
consequences. The manner in which these populations respond to such alterations in their …
consequences. The manner in which these populations respond to such alterations in their …
Association between KCNJ11 rs5219 polymorphisms and gestational diabetes mellitus: A meta-analysis
JK Muruganantham, I BK, R Veerabathiran - International Journal of …, 2024 - Springer
Background Gestational diabetes mellitus (GDM), characterized by hyperglycemia during
pregnancy, is influenced by various factors, including genetic predisposition. The potassium …
pregnancy, is influenced by various factors, including genetic predisposition. The potassium …