Risk factors for progression of age‐related macular degeneration

TJ Heesterbeek, L Lorés‐Motta… - Ophthalmic and …, 2020 - Wiley Online Library
Purpose Age‐related macular degeneration (AMD) is a degenerative disease of the macula,
often leading to progressive vision loss. The rate of disease progression can vary among …

The pathomechanism, antioxidant biomarkers, and treatment of oxidative stress-related eye diseases

YJ Hsueh, YN Chen, YT Tsao, CM Cheng… - International Journal of …, 2022 - mdpi.com
Oxidative stress is an important pathomechanism found in numerous ocular degenerative
diseases. To provide a better understanding of the mechanism and treatment of …

Sources, health benefits, and biological properties of zeaxanthin

A Bouyahya, N El Omari, M Hakkur… - Trends in Food Science …, 2021 - Elsevier
Background Zeaxanthin is a carotenoid pigment found in several fruits and vegetables.
Belonging to the xanthophyll family, it is widely present in human and some animals skin …

What do we know about the macular pigment in AMD: the past, the present, and the future

R Arunkumar, CM Calvo, CD Conrady, PS Bernstein - Eye, 2018 - nature.com
Carotenoids are lipophilic isoprenoid pigments with a common C40H56 core chemical
structure that are naturally synthesized by many plants, algae, bacteria, and fungi. Humans …

Optical assessment of skin carotenoid status as a biomarker of vegetable and fruit intake

IV Ermakov, M Ermakova, M Sharifzadeh… - Archives of biochemistry …, 2018 - Elsevier
Resonance Raman spectroscopy (RRS) and reflection spectroscopy (RS) are optical
methods applicable to the non-invasive detection of carotenoids in human skin. RRS is the …

Goji berry intake increases macular pigment optical density in healthy adults: A randomized pilot trial

X Li, RR Holt, CL Keen, LS Morse, G Yiu, RM Hackman - Nutrients, 2021 - mdpi.com
Age-related macular degeneration (AMD) is the third leading cause of blindness worldwide.
Macular pigment optical density (MPOD), a biomarker for AMD, is a non-invasive measure to …

Carotenoids in human skin

S Zerres, W Stahl - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2020 - Elsevier
The skin is shielding our organism from exogenous threats including solar radiation.
Carotenoids which are ingested with the diet accumulate in the skin with the highest levels …

Raman spectroscopy of carotenoid compounds for clinical applications—a review

J Udensi, J Loughman, E Loskutova, HJ Byrne - Molecules, 2022 - mdpi.com
Carotenoid compounds are ubiquitous in nature, providing the characteristic colouring of
many algae, bacteria, fruits and vegetables. They are a critical component of the human diet …

[HTML][HTML] Criterion-related validity of spectroscopy-based skin carotenoid measurements as a proxy for fruit and vegetable intake: a systematic review

MD Radtke, SJ Pitts, L Jahns, GC Firnhaber… - Advances in …, 2020 - Elsevier
Carotenoids are a category of health-promoting phytonutrients that are found in a variety of
fruits and vegetables and have been used as a biomarker to approximate dietary fruit and …

[HTML][HTML] Topographic distribution and progression of soft drusen volume in age-related macular degeneration implicate neurobiology of fovea

A Pollreisz, GS Reiter, H Bogunovic… - … & Visual Science, 2021 - jov.arvojournals.org
Purpose: To refine estimates of macular soft drusen abundance in eyes with age-related
macular degeneration (AMD) and evaluate hypotheses about drusen biogenesis, we …