[HTML][HTML] NODDI in clinical research

K Kamiya, M Hori, S Aoki - Journal of neuroscience methods, 2020 - Elsevier
Diffusion MRI (dMRI) has proven to be a useful imaging approach for both clinical diagnosis
and research investigating the microstructures of nervous tissues, and it has helped us to …

On modeling

DS Novikov, VG Kiselev… - Magnetic resonance in …, 2018 - Wiley Online Library
Mapping tissue microstructure with MRI holds great promise as a noninvasive window into
tissue organization at the cellular level. Having originated within the realm of diffusion NMR …

Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation

DS Novikov, E Fieremans, SN Jespersen… - NMR in …, 2019 - Wiley Online Library
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

Imaging brain microstructure with diffusion MRI: practicality and applications

DC Alexander, TB Dyrby, M Nilsson… - NMR in …, 2019 - Wiley Online Library
This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

[HTML][HTML] SANDI: a compartment-based model for non-invasive apparent soma and neurite imaging by diffusion MRI

M Palombo, A Ianus, M Guerreri, D Nunes… - Neuroimage, 2020 - Elsevier
This work introduces a compartment-based model for apparent cell body (namely soma) and
neurite density imaging (SANDI) using non-invasive diffusion-weighted MRI (DW-MRI). The …

Degeneracy in model parameter estimation for multi‐compartmental diffusion in neuronal tissue

IO Jelescu, J Veraart, E Fieremans… - NMR in …, 2016 - Wiley Online Library
The ultimate promise of diffusion MRI (dMRI) models is specificity to neuronal microstructure,
which may lead to distinct clinical biomarkers using noninvasive imaging. While multi …

Noninvasive quantification of axon radii using diffusion MRI

J Veraart, D Nunes, U Rudrapatna, E Fieremans… - elife, 2020 - elifesciences.org
Axon caliber plays a crucial role in determining conduction velocity and, consequently, in the
timing and synchronization of neural activation. Noninvasive measurement of axon radii …

[HTML][HTML] Neurite Exchange Imaging (NEXI): A minimal model of diffusion in gray matter with inter-compartment water exchange

IO Jelescu, A de Skowronski, F Geffroy, M Palombo… - NeuroImage, 2022 - Elsevier
Biophysical models of diffusion in white matter have been center-stage over the past two
decades and are essentially based on what is now commonly referred to as the “Standard …

Design and validation of diffusion MRI models of white matter

IO Jelescu, MD Budde - Frontiers in physics, 2017 - frontiersin.org
Diffusion MRI is arguably the method of choice for characterizing white matter microstructure
in vivo. Over the typical duration of diffusion encoding, the displacement of water molecules …

[HTML][HTML] Challenges for biophysical modeling of microstructure

IO Jelescu, M Palombo, F Bagnato… - Journal of Neuroscience …, 2020 - Elsevier
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …