Transposable element regulation and expression in cancer
EE Grundy, N Diab, KB Chiappinelli - The FEBS journal, 2022 - Wiley Online Library
Approximately 45% of the human genome is composed of transposable elements (TEs).
Expression of these elements is tightly regulated during normal development. TEs may be …
Expression of these elements is tightly regulated during normal development. TEs may be …
Integration of TE induces cancer specific alternative splicing events
WR Kim, EG Park, YJ Lee, WH Bae, DH Lee… - International Journal of …, 2022 - mdpi.com
Alternative splicing of messenger RNA (mRNA) precursors contributes to genetic diversity by
generating structurally and functionally distinct transcripts. In a disease state, alternative …
generating structurally and functionally distinct transcripts. In a disease state, alternative …
State‐of‐the‐art in transposable element modulation affected by drugs in malignant prostatic cancer cells
A Terrazzan, R Vanini, P Ancona… - Journal of Cellular …, 2024 - Wiley Online Library
Over recent years, the investigation of transposable elements (TEs) has granted researchers
a deeper comprehension of their characteristics and functions, particularly regarding their …
a deeper comprehension of their characteristics and functions, particularly regarding their …
Retrotransposon-derived transcripts and their functions in immunity and disease
MT Ueda - Genes & Genetic Systems, 2024 - jstage.jst.go.jp
Retrotransposons, which account for approximately 42% of the human genome, have been
increasingly recognized as “non-self” pathogen-associated molecular patterns (PAMPs) due …
increasingly recognized as “non-self” pathogen-associated molecular patterns (PAMPs) due …