Recent advances in small-molecule fluorescent probes for diagnosis of cancer cells/tissues

K Wang, C Liu, H Zhu, Y Zhang, M Su, X Wang… - Coordination Chemistry …, 2023 - Elsevier
Cancer has always been covetous to the health of human beings, and countless people die
every year due to cancer. Accurate diagnosis of cancer is an important prerequisite for its …

Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy

S Wang, L Gai, Y Chen, X Ji, H Lu, Z Guo - Chemical Society Reviews, 2024 - pubs.rsc.org
Mitochondria are essential for a diverse array of biological functions. There is increasing
research focus on developing efficient tools for mitochondria-targeted detection and …

Mitochondria-Targeting Multifunctional Fluorescent Probe toward Polarity, Viscosity, and ONOO and Cell Imaging

Y Huang, M Li, Q Zan, R Wang, S Shuang… - Analytical …, 2023 - ACS Publications
Abnormal changes occurring in the mitochondrial microenvironment are important markers
indicating mitochondrial and cell dysfunction. Herein, we designed and synthesized a …

Polarity-sensitive cell membrane probe reveals lower polarity of tumor cell membrane and its application for tumor diagnosis

Q Li, J Hong, S Feng, S Gong, G Feng - Analytical Chemistry, 2022 - ACS Publications
Cancer is a health threat worldwide, and it is urgent to develop more sensitive cancer
detection methods. Herein, a polarity-sensitive cell membrane probe (named COP) was …

Development of near-infrared mitochondrial polarity fluorescent probe for evaluating mitophagy in mice heart and potential cancer diagnosis

T Zhang, F Huo, W Zhang, F Cheng, C Yin - Chemical Engineering Journal, 2022 - Elsevier
Mitophagy is a process that selectively removes excess or damaged mitochondria, and
regulates the number of mitochondria in the cell to maintain the normal mitochondrial …

Two water-soluble and wash-free fluorogenic probes for specific lighting up cancer cell membranes and tumors

S Feng, Y Liu, Q Li, Z Gui, G Feng - Analytical Chemistry, 2022 - ACS Publications
The construction of microenvironment-sensitive probes with good cell membrane-
targetability can reveal the fundamental properties of cell membranes. Herein, two polarity …

Lipid Droplet-Specific Dual-Response Fluorescent Probe for the Detection of Polarity and H2O2 and Its Application in Living Cells

M Li, B Wang, J Liu, Z Zhang, L Chen, Y Li… - Analytical …, 2022 - ACS Publications
H2O2 and polarity are quite important in many physiological and pathological processes,
and their relationship is complicated and obscure for researchers. Thus, it is vital and …

Real-time imaging of acute alcoholic liver injury in vivo via a robust viscosity probe with aggregation-induced emission nature

Y Feng, G Nie, W Liang, W Li, Y Zhang, K Wang… - Sensors and Actuators B …, 2022 - Elsevier
As the early stage of alcoholic liver disease, acute alcoholic liver injury (AALI) is usually
ignored or misdiagnosed due to the lack of typical clinic symptoms, however, it will probably …

A benzothiazole derivative for differentiating mitochondrial G-quadruplex formation between normal and tumor cells

R Sun, H Sun, X Ye, D Yang, B Zhang, Y Liu… - Sensors and Actuators B …, 2024 - Elsevier
Emerging studies demonstrates that mitochondrial G-quadruplex (G4) may be a prospective
diagnostic and therapeutic target for cancer. Fluorescent probes targeting mitochondrial G4 …

Golgi polarity fluorescent imaging based on coumarin or 1, 8-naphthalimide derivatives in three channels

XC Feng, G Zhang, R Sun, YJ Xu, JF Ge - Sensors and Actuators B …, 2023 - Elsevier
As a key parameter affecting the biochemical reaction of cells, the change of polarity also
affects some important biological processes of cells. However, there are very few polarity …