Global signatures of protein and mRNA expression levels
Cellular states are determined by differential expression of the cell's proteins. The
relationship between protein and mRNA expression levels informs about the combined …
relationship between protein and mRNA expression levels informs about the combined …
A framework for understanding gene expression plasticity and its influence on stress tolerance
Phenotypic plasticity can serve as a stepping stone towards adaptation. Recently, studies
have shown that gene expression contributes to emergent stress responses such as thermal …
have shown that gene expression contributes to emergent stress responses such as thermal …
Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system
Differential mRNA expression studies implicitly assume that changes in mRNA expression
have biological meaning, most likely mediated by corresponding changes in protein levels …
have biological meaning, most likely mediated by corresponding changes in protein levels …
Integrated analysis of transcriptomic and proteomic data
Until recently, understanding the regulatory behavior of cells has been pursued through
independent analysis of the transcriptome or the proteome. Based on the central dogma, it …
independent analysis of the transcriptome or the proteome. Based on the central dogma, it …
Practical and robust identification of molecular subtypes in colorectal cancer by immunohistochemistry
Purpose: Recent transcriptomic analyses have identified four distinct molecular subtypes of
colorectal cancer with evident clinical relevance. However, the requirement for sufficient …
colorectal cancer with evident clinical relevance. However, the requirement for sufficient …
The progress of multi-omics technologies: determining function in lactic acid bacteria using a systems level approach
Lactic Acid Bacteria (LAB) have long been recognized as having a significant impact
ranging from commercial to health domains. A vast amount of research has been carried out …
ranging from commercial to health domains. A vast amount of research has been carried out …
Disease-specific, neurosphere-derived cells as models for brain disorders
N Matigian, G Abrahamsen… - Disease models & …, 2010 - journals.biologists.com
There is a pressing need for patient-derived cell models of brain diseases that are relevant
and robust enough to produce the large quantities of cells required for molecular and …
and robust enough to produce the large quantities of cells required for molecular and …
Gene expression plasticity in response to salinity acclimation in threespine stickleback ecotypes from different salinity habitats
Phenotypic plasticity is thought to facilitate the colonization of novel environments and
shape the direction of evolution in colonizing populations. However, the relative prevalence …
shape the direction of evolution in colonizing populations. However, the relative prevalence …
[HTML][HTML] EMT-like circulating tumor cells in ovarian cancer patients are enriched by platinum-based chemotherapy
I Chebouti, S Kasimir-Bauer, P Buderath… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background Assuming that tumor cell dissemination requires a shift to a mesenchymal
phenotype, we analyzed the incidence of epithelial-to-mesenchymal-transition (EMT)-like …
phenotype, we analyzed the incidence of epithelial-to-mesenchymal-transition (EMT)-like …
Chronic social stress during adolescence induces cognitive impairment in aged mice
V Sterlemann, G Rammes, M Wolf, C Liebl… - …, 2010 - Wiley Online Library
Age‐related cognitive decline is one of the major aspects that impede successful aging in
humans. Environmental factors, such as chronic stress, can accelerate or aggravate …
humans. Environmental factors, such as chronic stress, can accelerate or aggravate …