Stroke is the second highest cause of death globally and a leading cause of disability, with
an increasing incidence in developing countries. Ischaemic stroke caused by arterial …

Stroke is the leading cause of long term disability in developed countries and one of the top
causes of mortality worldwide. The past decade has seen substantial advances in the …

Background The role of endovascular therapy for acute stroke with a large infarction has not
been extensively studied in differing populations. Methods We conducted a multicenter …

Background Trials of the efficacy and safety of endovascular thrombectomy in patients with
large ischemic strokes have been carried out in limited populations. Methods We performed …

Background Endovascular therapy for acute ischemic stroke is generally avoided when the
infarction is large, but the effect of endovascular therapy with medical care as compared with …

Background Mechanical thrombectomy (MT) has become the cornerstone of acute ischemic
stroke management in patients with large vessel occlusion (LVO). Objective To assist …

Background The COVID-19 pandemic led to profound changes in the organization of health
care systems worldwide. Aims We sought to measure the global impact of the COVID-19 …

Importance For patients with large vessel occlusion strokes, it is unknown whether
endovascular treatment alone compared with intravenous thrombolysis plus endovascular …

Importance Clinical evidence of the potential treatment benefit of mechanical thrombectomy
for posterior circulation distal, medium vessel occlusion (DMVO) is sparse. Objective To …

Background Identifying the presence and extent of infarcted brain tissue at baseline plays a
crucial role in the treatment of patients with acute ischemic stroke (AIS). Patients with …