The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

Background Antimicrobial peptides (AMPs) can act on the bacterial cell membrane to play
an antibacterial role in types of drug-resistant bacteria. Therefore, AMPs have attracted more …

The amyloid β (Aβ) peptide and its shorter variants, including a highly cytotoxic Aβ25–35
peptide, exert their neurotoxic effect during Alzheimer's disease by various mechanisms …

The activity of antimicrobial peptides stems from their interaction with bacterial membranes,
which are disrupted according to a number of proposed mechanisms. Here, we investigate …

Bacterial infections in humans and animals caused by multidrug-resistant (MDR) pathogens
pose a serious threat to public health. New antibacterial targets are extremely urgent to …

Understanding the mechanism by which an antibacterial agent interacts with a model
membrane provides vital information for better design of future antibiotics. In this study, we …

With the increasing number of drug-resistant bacteria, there is an urgent need for new
antimicrobial agents, and antimicrobial peptides (AMPs), which exist in the human non …

BP100 is a short antimicrobial peptide and can also act as a molecule-carrier into cells. Like
with other antimicrobial peptides, the precise mechanism of membrane disruption is not fully …

Antimicrobial peptides are innate host defense molecules with the ability to kill pathogens.
They have been widely studied for their membrane lytic activity and their potential to …

The present work compares the interaction of the antibiotic levofloxacin (LVX) with
zwitterionic and anionic liposomes composed of 1, 2-dipalmitoyl-sn-glycero-3 …