Here, there, and everywhere: The importance of ER membrane contact sites
H Wu, P Carvalho, GK Voeltz - Science, 2018 - science.org
BACKGROUND The defining feature of eukaryotic cells is the presence of membrane-bound
organelles of diverse kinds, each with specialized functions. Most organelles have multiple …
organelles of diverse kinds, each with specialized functions. Most organelles have multiple …
Calcium signalling in T cells
M Trebak, JP Kinet - Nature Reviews Immunology, 2019 - nature.com
Abstract Calcium (Ca2+) signalling is of paramount importance to immunity. Regulated
increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex …
increases in cytosolic and organellar Ca2+ concentrations in lymphocytes control complex …
[HTML][HTML] Intracellular Ca2+ sensing: its role in calcium homeostasis and signaling
R Bagur, G Hajnóczky - Molecular cell, 2017 - cell.com
Ca 2+ is a ubiquitous intracellular messenger that controls diverse cellular functions but can
become toxic and cause cell death. Selective control of specific targets depends on …
become toxic and cause cell death. Selective control of specific targets depends on …
The role of calcium–calcineurin–NFAT signaling pathway in health and autoimmune diseases
Calcium (Ca2+) is an essential signaling molecule that controls a wide range of biological
functions. In the immune system, calcium signals play a central role in a variety of cellular …
functions. In the immune system, calcium signals play a central role in a variety of cellular …
[HTML][HTML] A micropeptide encoded by a putative long noncoding RNA regulates muscle performance
DM Anderson, KM Anderson, CL Chang… - Cell, 2015 - cell.com
Functional micropeptides can be concealed within RNAs that appear to be noncoding. We
discovered a conserved micropeptide, which we named myoregulin (MLN), encoded by a …
discovered a conserved micropeptide, which we named myoregulin (MLN), encoded by a …
CRAC channels and calcium signaling in T cell-mediated immunity
Calcium (Ca 2+) signals play fundamental roles in immune cell function. The main sources
of Ca 2+ influx in mammalian lymphocytes following antigen receptor stimulation are Ca 2+ …
of Ca 2+ influx in mammalian lymphocytes following antigen receptor stimulation are Ca 2+ …
Mast cell function: a new vision of an old cell
EZM da Silva, MC Jamur… - Journal of Histochemistry …, 2014 - journals.sagepub.com
Since first described by Paul Ehrlich in 1878, mast cells have been mostly viewed as
effectors of allergy. It has been only in the past two decades that mast cells have gained …
effectors of allergy. It has been only in the past two decades that mast cells have gained …
Why calcium? How calcium became the best communicator
E Carafoli, J Krebs - Journal of Biological Chemistry, 2016 - ASBMB
Calcium carries messages to virtually all important functions of cells. Although it was already
active in unicellular organisms, its role became universally important after the transition to …
active in unicellular organisms, its role became universally important after the transition to …
Store-operated calcium channels
M Prakriya, RS Lewis - Physiological reviews, 2015 - journals.physiology.org
Store-operated calcium channels (SOCs) are a major pathway for calcium signaling in
virtually all metozoan cells and serve a wide variety of functions ranging from gene …
virtually all metozoan cells and serve a wide variety of functions ranging from gene …
Ca2+ homeostasis and endoplasmic reticulum (ER) stress: An integrated view of calcium signaling
J Krebs, LB Agellon, M Michalak - Biochemical and biophysical research …, 2015 - Elsevier
Cellular Ca 2+ homeostasis is maintained through the integrated and coordinated function
of Ca 2+ transport molecules, Ca 2+ buffers and sensors. These molecules are associated …
of Ca 2+ transport molecules, Ca 2+ buffers and sensors. These molecules are associated …