Adverse effects of antidepressant medications and their management in children and adolescents
Introduction Selective serotonin reuptake inhibitors (SSRIs) and, to a lesser extent, serotonin‐
norepinephrine reuptake inhibitors (SNRIs) are the cornerstone of pharmacotherapy for …
norepinephrine reuptake inhibitors (SNRIs) are the cornerstone of pharmacotherapy for …
Cannabinoids and drug metabolizing enzymes: Potential for drug-drug interactions and implications for drug safety and efficacy
Introduction Cannabis is an increasingly popular recreational and medicinal drug in the
USA. While cannabis is still a Schedule 1 drug federally, many states have lifted the ban on …
USA. While cannabis is still a Schedule 1 drug federally, many states have lifted the ban on …
Cannabidiol for treatment-resistant anxiety disorders in young people: an open-label trial
Background: Treatment resistance is a significant problem among young people
experiencing moderate-to-severe anxiety, affecting nearly half of all patients. This study …
experiencing moderate-to-severe anxiety, affecting nearly half of all patients. This study …
Cannabinoid interactions with cytochrome P450 drug metabolism: a full-spectrum characterization
Medicinal cannabis use has increased exponentially with widespread legalization around
the world. Cannabis-based products are being used for numerous health conditions, often in …
the world. Cannabis-based products are being used for numerous health conditions, often in …
Cannabidiol (CBD) dosing: Plasma pharmacokinetics and effects on accumulation in skeletal muscle, liver and adipose tissue
RB Child, MJ Tallon - Nutrients, 2022 - mdpi.com
Oral cannabidiol (CBD) consumption is widespread in North America and Europe, as it has
analgesic, neuroprotective and antitumor effects. Although oral CBD consumption in …
analgesic, neuroprotective and antitumor effects. Although oral CBD consumption in …
Comprehensive predictions of cytochrome P450 (P450)-mediated in vivo cannabinoid-drug interactions based on reversible and time-dependent P450 inhibition in …
S Bansal, MF Paine, JD Unadkat - Drug Metabolism and Disposition, 2022 - ASPET
We previously reported the unbound reversible (IC50, u) and time-dependent (KI, u)
inhibition potencies of cannabidiol (CBD), delta-9-tetrahydrocannabinol (THC), and THC …
inhibition potencies of cannabidiol (CBD), delta-9-tetrahydrocannabinol (THC), and THC …
Contemplating cannabis? The complex relationship between cannabinoids and hepatic metabolism resulting in the potential for drug-drug interactions
RT Smith, SA Gruber - Frontiers in Psychiatry, 2023 - frontiersin.org
The majority of states have fully legalized the use of medical cannabis (MC), and nearly all
other states allow limited access to cannabidiol (CBD), a non-intoxicating constituent of …
other states allow limited access to cannabidiol (CBD), a non-intoxicating constituent of …
Cannabis for Medical Use: Analysis of Recent Clinical Trials in View of Current Legislation
F Baratta, I Pignata, L Ravetto Enri… - Frontiers in …, 2022 - frontiersin.org
Cannabis has long been regarded as a recreational substance in the Western world. The
recent marketing authorization of some medicinal products of industrial origin and the …
recent marketing authorization of some medicinal products of industrial origin and the …
Cannabinoids, insomnia, and other sleep disorders
Sleep disturbances are often cited as a primary reason for medicinal cannabis use, and
there is increasing clinical interest in the therapeutic potential of cannabinoids in treating …
there is increasing clinical interest in the therapeutic potential of cannabinoids in treating …
Cannabidiol drug interaction considerations for prescribers and pharmacists
Introduction In light of the widespread use of non-prescribed and prescribed cannabidiol, the
use of cannabidiol with other medications is likely, and this may result in drug interactions …
use of cannabidiol with other medications is likely, and this may result in drug interactions …