The progressive degeneration of the skeletal musculature in Duchenne muscular dystrophy
is accompanied by reactive myofibrosis, fat substitution, and chronic inflammation. Fibrotic …

Mass spectrometry-based proteomics is a sophisticated identification tool specializing in
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …

The analysis of cells and tissue by bottom-up proteomics starts with lysis, followed by in-
solution digestion. Lysis buffers commonly used include detergents and other reagents for …

The extracellular matrix is a key component of tissues, yet it is underrepresented in
proteomic datasets. Identification and evaluation of proteins in the extracellular matrix (ECM) …

The extracellular matrix (ECM) is unique to each tissue and capable of guiding cell
differentiation, migration, morphology, and function. The ECM proteome of different …

The rapidly‐advancing field of pharmaceutical and clinical research calls for systematic,
molecular‐level characterization of complex biological systems. To this end, quantitative …

Introduction The matrisome and adhesome comprise proteins that are found within or are
associated with the extracellular matrix (ECM) and adhesion complexes, respectively …

Extracellular matrix (ECM) is an important component of the pancreatic microenvironment
which regulates β cell proliferation, differentiation, and insulin secretion. Protocols have …

The pancreas is a vital organ with digestive and endocrine roles, and diseases of the
pancreas affect millions of people yearly. A better understanding of the pancreas proteome …

The rod-outer-segment guanylyl cyclase 1 (ROS-GC1) is a key transmembrane protein for
retinal phototransduction. Mutations of ROS-GC1 correlate with different retinal diseases that …