Spectral-domain OCT measurements in Alzheimer's disease: a systematic review and meta-analysis

VTT Chan, Z Sun, S Tang, LJ Chen, A Wong, CC Tham… - Ophthalmology, 2019 - Elsevier
Topic OCT is a noninvasive tool to measure specific retinal layers in the eye. The
relationship of retinal spectral-domain (SD) OCT measurements with Alzheimer's disease …

Impact of diabetes on cognitive function and brain structure

A Moheet, S Mangia… - Annals of the New York …, 2015 - Wiley Online Library
Both type 1 and type 2 diabetes have been associated with reduced performance on
multiple domains of cognitive function and with structural abnormalities in the brain. With an …

Indian diabetic retinopathy image dataset (IDRiD): a database for diabetic retinopathy screening research

P Porwal, S Pachade, R Kamble, M Kokare… - Data, 2018 - mdpi.com
Diabetic Retinopathy is the most prevalent cause of avoidable vision impairment, mainly
affecting the working-age population in the world. Recent research has given a better …

Retinal pathological features and proteome signatures of Alzheimer's disease

Y Koronyo, A Rentsendorj, N Mirzaei, GC Regis… - Acta …, 2023 - Springer
Alzheimer's disease (AD) pathologies were discovered in the accessible neurosensory
retina. However, their exact nature and topographical distribution, particularly in the early …

[HTML][HTML] Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer's disease

Y Koronyo, D Biggs, E Barron, DS Boyer, JA Pearlman… - JCI insight, 2017 - ncbi.nlm.nih.gov
BACKGROUND. Noninvasive detection of Alzheimer's disease (AD) with high specificity and
sensitivity can greatly facilitate identification of at-risk populations for earlier, more effective …

The p factor: one general psychopathology factor in the structure of psychiatric disorders?

A Caspi, RM Houts, DW Belsky… - Clinical …, 2014 - journals.sagepub.com
Mental disorders traditionally have been viewed as distinct, episodic, and categorical
conditions. This view has been challenged by evidence that many disorders are sequentially …

Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease

X Hadoux, F Hui, JKH Lim, CL Masters, A Pébay… - Nature …, 2019 - nature.com
Studies of rodent models of Alzheimer's disease (AD) and of human tissues suggest that the
retinal changes that occur in AD, including the accumulation of amyloid beta (Aβ), may serve …

[HTML][HTML] Retinal vessel diameters and function in cardiovascular risk and disease

H Hanssen, L Streese, W Vilser - Progress in retinal and eye research, 2022 - Elsevier
In the last two decades evidence has gradually accumulated suggesting that the eye may be
a unique window for cardiovascular risk stratification based on the assessment of subclinical …

The retina as a window to the brain—from eye research to CNS disorders

A London, I Benhar, M Schwartz - Nature Reviews Neurology, 2013 - nature.com
Philosophers defined the eye as a window to the soul long before scientists addressed this
cliché to determine its scientific basis and clinical relevance. Anatomically and …

[HTML][HTML] Diabetes mellitus and cognitive impairments

E Saedi, MR Gheini, F Faiz, MA Arami - World journal of diabetes, 2016 - ncbi.nlm.nih.gov
There is strong evidence that diabetes mellitus increases the risk of cognitive impairment
and dementia. Insulin signaling dysregulation and small vessel disease in the base of …