Physical stimuli are essential for the function of eukaryotic cells, and changes in physical
signals are important elements in normal tissue development as well as in disease initiation …

Body implants and implantable medical devices have dramatically improved and prolonged
the life of countless patients. However, our body repair mechanisms have evolved to isolate …

Macrophages are tissue-resident immune cells that play a critical role in maintaining
homeostasis and fighting infection. In addition, these cells are involved in the progression of …

In this review, we compare the reported values of Young's modulus (YM) obtained from
indentation and tensile deformations of soft biological tissues. When the method of …

Although biochemical signals that modulate stem cell self-renewal and differentiation were
extensively studied, only recently were the mechanical properties of a stem cell's …

Diabetes mellitus is a worldwide epidemic characterized by chronic hyperglycemia that
results from either a deficiency or tolerance in insulin. 1 In the United States, 8.3% of the …

Current strategies to limit macrophage adhesion, fusion and fibrous capsule formation in the
foreign body response have focused on modulating material surface properties. We …

Silicate bioceramics have been considered to possess a wide prospect of clinical
application for orthopedic tissue regeneration due to their excellent osteogenesis and …

Macrophages and dendritic cells are myeloid cells that play critical roles in immune
responses. Macrophages help to maintain homeostasis through tissue regeneration and the …

Implanted bone scaffolds often fail to successfully integrate with the host tissue because they
do not elicit a favorable immune reaction. Properties of bone scaffold not only provide …