Coronary microvascular dysfunction

PG Camici, F Crea - New England Journal of Medicine, 2007 - Mass Medical Soc
This review discusses the pathogenesis and management of coronary microvascular
dysfunction. Factors to consider in clinical management are the cause of the dysfunction and …

Doppler echocardiography assessment of coronary microvascular function in patients with angina and no obstructive coronary artery disease

J Schroder, E Prescott - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Echocardiographic evaluation is an essential part of the diagnostic work-up in patients with
known or suspected cardiovascular disease. Transthoracic Doppler echocardiography …

Coronary flow reserve is reduced in young men with IDDM

OP Pitkänen, P Nuutila, OT Raitakari, T Rönnemaa… - Diabetes, 1998 - Am Diabetes Assoc
Disturbances of coronary circulation have been reported in diabetic patients with
microvascular complications but without obstructive coronary atherosclerosis. The aim of the …

Low density lipoprotein cholesterol and coronary microvascular dysfunction in hypercholesterolemia

PA Kaufmann, T Gnecchi-Ruscone, KP Schäfers… - Journal of the American …, 2000 - jacc.org
OBJECTIVES The present study evaluates the impact of total cholesterol (TC) and its
subfractions on coronary flow reserve (CFR), an index of the integrated function of the …

Early impairment of coronary flow reserve in young men with borderline hypertension

H Laine, OT Raitakari, H Niinikoski, OP Pitkänen… - Journal of the American …, 1998 - jacc.org
Objectives. The purpose of this study was to investigate whether functional abnormalities in
coronary vasomotion are present in young healthy asymptomatic men fulfilling the World …

Improvement in coronary flow reserve determined by positron emission tomography after 6 months of cholesterol-lowering therapy in patients with early stages of …

D Baller, G Notohamiprodjo, U Gleichmann… - Circulation, 1999 - Am Heart Assoc
Background—Early stages of coronary atherosclerosis are characterized by a mainly
functional impairment of coronary vasodilator capacity under the impact of such risk factors …

Sex differences in the coronary system

VR Taqueti - Sex-Specific Analysis of Cardiovascular Function, 2018 - Springer
Cardiovascular disease remains the leading cause of morbidity and mortality for both
women and men. Emerging evidence supports that ischemic heart disease (IHD) may …

Free fatty acids induce insulin resistance in both cardiac and skeletal muscle microvasculature in humans

J Liu, LA Jahn, DE Fowler, EJ Barrett… - The Journal of …, 2011 - academic.oup.com
abstract Context: Insulin recruits microvasculature in both cardiac and skeletal muscle,
which increases the endothelial exchange surface area. Plasma concentrations of free fatty …

Relative myocardial blood flow by dynamic computed tomographic perfusion imaging predicts hemodynamic significance of coronary stenosis better than absolute …

AK Kono, A Coenen, M Lubbers, A Kurata… - Investigative …, 2014 - journals.lww.com
Objectives Quantitative myocardial perfusion imaging by computed tomography (CT) was
recently introduced to calculate myocardial blood flow (MBF). Because absolute MBF …

Current perspectives in coronary microvascular dysfunction

JS Shome, D Perera, S Plein, A Chiribiri - Microcirculation, 2017 - Wiley Online Library
The coronary arterial system consists of large epicardial coronary arteries, pre‐arterioles,
and arterioles, which together closely regulate CBF. Structural, functional, and extravascular …