Advances in microfluidics: technical innovations and applications in diagnostics and therapeutics
Microfluidics describes the study of systems that operate fluids at miniature scales, often in
microchannels. It is powerful in scaling down biological experiments by many orders of …
microchannels. It is powerful in scaling down biological experiments by many orders of …
Microfluidic technologies for cell deformability cytometry
Microfluidic detection methods for cell deformability cytometry have been regarded as
powerful tools for single‐cell analysis of cellular mechanical phenotypes, thus having been …
powerful tools for single‐cell analysis of cellular mechanical phenotypes, thus having been …
Impedance‐Based Multimodal Electrical‐Mechanical Intrinsic Flow Cytometry
Reflecting various physiological states and phenotypes of single cells, intrinsic biophysical
characteristics (eg, mechanical and electrical properties) are reliable and important, label …
characteristics (eg, mechanical and electrical properties) are reliable and important, label …
Poly (ethylene oxide) concentration gradient-based microfluidic isolation of circulating tumor cells
Y Cheng, S Zhang, L Qin, J Zhao, H Song… - Analytical …, 2023 - ACS Publications
Circulating tumor cells (CTCs) have emerged as promising circulating biomarkers for non-
invasive cancer diagnosis and management. Isolation and detection of CTCs in clinical …
invasive cancer diagnosis and management. Isolation and detection of CTCs in clinical …
[HTML][HTML] Selectable encapsulated cell quantity in droplets via label-free electrical screening and impedance-activated sorting
Single-cell encapsulation in droplets has become a powerful tool in immunotherapy,
medicine discovery, and single-cell analysis, thanks to its capability for cell confinement in …
medicine discovery, and single-cell analysis, thanks to its capability for cell confinement in …
Submicron-precision particle characterization in microfluidic impedance cytometry with double differential electrodes
Submicron-precision particle characterization is crucial for counting, sizing and identifying a
variety of biological particles, such as bacteria and apoptotic bodies. Microfluidic impedance …
variety of biological particles, such as bacteria and apoptotic bodies. Microfluidic impedance …
Inertial microfluidics for high-throughput cell analysis and detection: a review
Z Zhou, Y Chen, S Zhu, L Liu, Z Ni, N Xiang - Analyst, 2021 - pubs.rsc.org
Since it was first proposed in 2007, inertial microfluidics has been extensively studied in
terms of theory, design, fabrication, and application. In recent years, with the rapid …
terms of theory, design, fabrication, and application. In recent years, with the rapid …
Machine learning empowered multi-stress level electromechanical phenotyping for high-dimensional single cell analysis
Microfluidics provides a powerful platform for biological analysis by harnessing the ability to
precisely manipulate fluids and microparticles with integrated microsensors. Here, we …
precisely manipulate fluids and microparticles with integrated microsensors. Here, we …
Impedance‐enabled camera‐free intrinsic mechanical cytometry
Mechanical properties of single cells are important label‐free biomarkers normally
measured by expensive and complex imaging systems. To unlock this limit and allow …
measured by expensive and complex imaging systems. To unlock this limit and allow …
High-throughput adjustable deformability cytometry utilizing elasto-inertial focusing and virtual fluidic channel
Z Zhou, C Ni, Z Zhu, Y Chen, Z Ni, N Xiang - Lab on a Chip, 2023 - pubs.rsc.org
Cell mechanical properties provide a label-free marker for indicating cell states and disease
processes. Although microfluidic deformability cytometry has demonstrated great potential …
processes. Although microfluidic deformability cytometry has demonstrated great potential …