[HTML][HTML] Recent advances in selective and targeted drug/gene delivery systems using cell-penetrating peptides

SH Nam, J Park, H Koo - Archives of Pharmacal Research, 2023 - Springer
Biological cell membranes are a natural barrier for living cells. In the last few decades, the
cell membrane has been the main hurdle in the efficient delivery of bioactive and therapeutic …

[HTML][HTML] Translocation of non-lytic antimicrobial peptides and bacteria penetrating peptides across the inner membrane of the bacterial envelope

J Frimodt-Møller, C Campion, PE Nielsen… - Current Genetics, 2022 - Springer
The increase in multidrug-resistant pathogenic bacteria has become a problem worldwide.
Currently there is a strong focus on the development of novel antimicrobials, including …

Cell-penetrating peptides

M Zorko, Ü Langel - Cell penetrating peptides: methods and protocols, 2022 - Springer
In this introductory chapter, we first define cell-penetrating peptides (CPPs), give short
overview of CPP history and discuss several aspects of CPP classification. Next section is …

Physical and mechanical cues affecting biomaterial-mediated plasmid DNA delivery: insights into non-viral delivery systems

V Graceffa - Journal of Genetic Engineering and Biotechnology, 2021 - Elsevier
Background Whilst traditional strategies to increase transfection efficiency of non-viral
systems aimed at modifying the vector or the polyplexes/lipoplexes, biomaterial-mediated …

[PDF][PDF] The mechanism underlying toxicity of a venom peptide against insects reveals how ants are master at disrupting membranes

S Ascoët, A Touchard, N Téné, B Lefranc, J Leprince… - Iscience, 2023 - cell.com
Hymenopterans represent one of the most abundant groups of venomous organisms but
remain little explored due to the difficult access to their venom. The development of proteo …

Nuclear localization signal peptides enhance genetic transformation of Dunaliella salina

S Feng, L Hu, A Li, S Li, Y Li, C Niu, B Wang… - Molecular Biology …, 2023 - Springer
Background Dunaliella salina (D. salina) expression system shows a very attractive
application prospect, but it currently has a technical bottleneck, namely the low or unstable …

A re-evaluation of the free energy profiles for cell-penetrating peptides across DOPC membranes

BT Kumara, NK Wijesiri, P Rathnayake… - International Journal of …, 2021 - Springer
Cell penetrating peptides (CPPs) hold immense potential for the transport of therapeutic
agents to their active targets, due to their low cytotoxicity and high transduction efficiency …

[HTML][HTML] hnRNPK-derived cell-penetrating peptide inhibits cancer cell survival

PK Puvvula, S Buczkowski, AM Moon - Molecular Therapy-Oncolytics, 2021 - cell.com
hnRNPK is a multifunctional protein that plays an important role in cancer cell proliferation
and metastasis via its RNA-and DNA-binding properties. Previously we showed that cell …

[HTML][HTML] NEO E-vita—NEO era!

H Jakob, F Mourad - Indian Journal of Thoracic and Cardiovascular …, 2022 - Springer
In this review article, the history of the first commercially available thoracic aortic hybrid graft,
the E-vita Open, later modified to the blood-impermeable E-vita Open Plus, is reported from …

Live Cell Imaging of Peptide Uptake Using a Microfluidic Platform

M Yuce, E Ozkirimli, B Sariyar Akbulut… - International Journal of …, 2021 - Springer
Cell penetrating peptides (CPPs) are unique molecules with the ability to pass through
biological membranes as they carry their cargoes into the cells. Endocytosis and direct …