[HTML][HTML] Biotechnological application of Streptomyces for the production of clinical drugs and other bioactive molecules

F Del Carratore, EKR Hanko, R Breitling… - Current Opinion in …, 2022 - Elsevier
Highlights•A rational optimization of Streptomyces strains is possible.•This can be achieved
through rewiring of primary metabolism and regulatory networks.•Biosynthetic gene cluster …

Diosmetin and tamarixetin (methylated flavonoids): A review on their chemistry, sources, pharmacology, and anticancer properties

EWC Chan, YK Ng, CY Tan, L Alessandro… - Journal of Applied …, 2021 - japsonline.com
This review begins with an introduction to the basic skeleton and classes of flavonoids.
Studies on flavonoids have shown that the presence or absence of their functional moieties …

[HTML][HTML] Production of (2S)-sakuranetin from (2S)-naringenin in Escherichia coli by strengthening methylation process and cell resistance

Q Sun, S Gao, S Yu, P Zheng, J Zhou - Synthetic and systems …, 2022 - Elsevier
Abstract (2S)-Sakuranetin is a 7-O-methylflavonoid that has anticancer, antiviral, and
antimicrobial activities. Methylation process is involved in biosynthesizing (2S)-sakuranetin …

Multiplex approach of metabolite and transcript profiling identify a biosynthetic mechanism for kayaflavone biosynthesis in Torreya grandis

Y Gao, C Wang, T Wu, Z Ma, W Chen, H Chang… - Industrial Crops and …, 2024 - Elsevier
Torreya grandis is a medicinal and edible food plant from southern China that is high in
flavonoids and other bioactive compounds. Among these, Torreya grandis-enriched …

Potential Therapeutic Targets of Quercetin in the Cutaneous Melanoma Model and Its Cellular Regulation Pathways: A Systematic Review

MTSF Salgado, E Fernandes e Silva… - Nutrition and …, 2023 - Taylor & Francis
Melanoma is a skin cancer with a high mortality rate due to its invasive characteristics.
Currently, immunotherapy and targeted therapy increase patient survival but are ineffective …

Research Progress of Tamarixetin and its Glycosides

C Li, M Tao, T Li, X Huang, H Sui… - Mini Reviews in …, 2024 - ingentaconnect.com
Tamarixetin and its glycosides are widely distributed in natural plants, and they are also
natural flavonoid derivatives of quercetin. Its main pharmacological effects include …