BACKGROUND: A minority of patients having cardiac procedures (15% to 20%) consume
more than 80% of the blood products transfused at operation. Blood must be viewed as a …

The development of blood storage systems allowed donation and transfusion to be
separated in time and space. This separation has permitted the regionalization of donor …

Background—Red blood cell transfusion can both benefit and harm. To inform decisions
about transfusion, we aimed to quantify associations of transfusion with clinical outcomes …

Background Hemoconcentration may be an important factor that determines the progression
of severe acute pancreatitis (SAP). In addition, it has been proposed that biomarkers may be …

Objective Cells require energy to carry out their functions and they typically use oxidative
phosphorylation to generate the needed ATP. Thus, cells have a continuous need for …

For many years, in daily clinical practice, the traditional 10/30 rule (hemoglobin 10 g/dL–
hematocrit 30%) has been the most commonly used trigger for blood transfusions. Over the …

In the past, anemia in the perioperative period has been treated by red blood cell (RBC)
transfusions relatively uncritically. RBC transfusions were believed to increase oxygen …

A number of clinical studies have associated acute anemia with cerebral injury in
perioperative patients. Evidence of such injury has been observed near the currently …

A small group of people belonging to a certain religion, called Jehovah's witness do not
accept blood transfusion or blood products, based on biblical readings. When such group of …

Objective To evaluate cardiovascular and respiratory effects and pharmacokinetics of a 24-
hour intravenous constant rate infusion (CRI) of dexmedetomidine (DMED) during and after …