Thermo-responsive polymers: Applications of smart materials in drug delivery and tissue engineering
Synthetic polymers are attracting great attention in the last decades for their use in the
biomedical field as nanovectors for controlled drug delivery, hydrogels and scaffolds …
biomedical field as nanovectors for controlled drug delivery, hydrogels and scaffolds …
[HTML][HTML] Poly (N-isopropylacrylamide)-based thermoresponsive surfaces provide new types of biomedical applications
Thermoresponsive surfaces, prepared by grafting of poly (N-isopropylacrylamide)(PIPAAm)
or its copolymers, have been investigated for biomedical applications. Thermoresponsive …
or its copolymers, have been investigated for biomedical applications. Thermoresponsive …
Ultrasoft electronics to monitor dynamically pulsing cardiomyocytes
In biointegrated electronics, the facile control of mechanical properties such as softness and
stretchability in electronic devices is necessary to minimize the perturbation of motions …
stretchability in electronic devices is necessary to minimize the perturbation of motions …
Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances
Engineered human cardiac tissues facilitate progress in regenerative medicine, disease
modelling and drug development. In this Perspective, we reflect on the most notable …
modelling and drug development. In this Perspective, we reflect on the most notable …
[HTML][HTML] Fabrication of scaffold-free tubular cardiac constructs using a Bio-3D printer
K Arai, D Murata, AR Verissimo, Y Mukae, M Itoh… - PloS one, 2018 - journals.plos.org
A major challenge in cardiac tissue engineering is the host's immune response to artificial
materials. To overcome this problem, we established a scaffold-free system for assembling …
materials. To overcome this problem, we established a scaffold-free system for assembling …
Thermally-triggered fabrication of cell sheets for tissue engineering and regenerative medicine
H Takahashi, T Okano - Advanced drug delivery reviews, 2019 - Elsevier
Cell transplantation is a promising approach for promoting tissue regeneration in the
treatment of damaged tissues or organs. Although cells have conventionally been delivered …
treatment of damaged tissues or organs. Although cells have conventionally been delivered …
[HTML][HTML] Contractile force measurement of human induced pluripotent stem cell-derived cardiac cell sheet-tissue
We have developed our original tissue engineering technology “cell sheet engineering”
utilizing temperature-responsive culture dishes. The cells are confluently grown on a …
utilizing temperature-responsive culture dishes. The cells are confluently grown on a …
[HTML][HTML] Antibody drug separation using thermoresponsive anionic polymer brush modified beads with optimised electrostatic and hydrophobic interactions
K Nagase, S Ishii, K Ikeda, S Yamada, D Ichikawa… - Scientific reports, 2020 - nature.com
Antibody drugs play an important role in biopharmaceuticals, because of the specificity for
target biomolecules and reduction of side effects. Thus, separation and analysis techniques …
target biomolecules and reduction of side effects. Thus, separation and analysis techniques …
[HTML][HTML] Pulsatile tubular cardiac tissues fabricated by wrapping human iPS cells-derived cardiomyocyte sheets
The purpose of this study was to fabricate pulsatile tubular cardiac tissue using cell sheet
based-tissue engineering. First, we fabricated human induced pluripotent stem cell (hiPSc) …
based-tissue engineering. First, we fabricated human induced pluripotent stem cell (hiPSc) …
A novel method to align cells in a cardiac tissue‐like construct fabricated by cell sheet‐based tissue engineering
J Homma, S Shimizu, H Sekine… - Journal of Tissue …, 2020 - Wiley Online Library
Fabrication of cardiac tissue from human induced pluripotent stem cell‐derived
cardiomyocytes (hiPS‐CMs) has received great interest, but a major challenge facing …
cardiomyocytes (hiPS‐CMs) has received great interest, but a major challenge facing …