When a molecule absorbs a photon of appropriate energy, a chain of photophysical events
ensues, such as internal conversion or vibrational relaxation (loss of energy in the absence …

This article presents an overview of time-resolved (lifetime) fluorescence techniques used in
biomedical diagnostics. In particular, we review the development of time-resolved …

Biological tissues are not uniquely composed of cells. A substantial part of their volume is
extracellular space, which is primarily filled by an intricate network of macromolecules …

There is an ever-increasing demand for new imaging methods that can provide additional
information about the coronary wall to better characterize and stratify high-risk plaques, and …

Fluorescence lifetime imaging (FLIm) is an optical spectroscopic imaging technique capable
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …

Fluorescence lifetime experiments are a standard approach for measuring excited-state
dynamics and local environmental effects. Here, we show that entangled photon pairs …

A compact clinically compatible fluorescence lifetime imaging microscopy (FLIM) system
was designed and built for intraoperative disease diagnosis and validated in vivo in a …

A clinically compatible fluorescence lifetime imaging microscopy (FLIM) system was
developed. The system was applied to intraoperative in vivo imaging of head and neck …

Comprehensive imaging of both the structural and biochemical characteristics of
atherosclerotic plaque is essential for the diagnosis and study of coronary artery disease …

There is an increasing interest in the application of fluorescence lifetime imaging (FLIM) for
medical diagnosis. Central to the clinical translation of FLIM technology is the development …