Development of novel derivatives to rein in and fight bacteria have never been more
demanding, as microbial resistance strains are alarmingly increasing. A multitude of new …

The colonization of bacterial pathogens is a major concern in wound infection and becoming
a public health issue. Herein, a core–shell structured Ag@ MSN (silver core embedded with …

Tuberculosis regimens currently applied in clinical practice require months of multidrug
therapy, which imposes a major challenge of patient compliance and drug resistance …

Leishmaniasis is a vector‐borne neglected parasitic infection affecting thousands of
individuals, mostly among populations in low‐to moderate‐income developing countries. In …

A novel series of N-acylated ciprofloxacin (CP) conjugates 1–21 were synthesized and
screened as potential antimicrobial agents. Conjugates 1 and 2 were 1.25–10-fold more …

For unmet clinical needs, a novel class of ethacrynic acid (EA) derivatives containing triazole
moieties (3a-i and 8) were designed, synthesized and evaluated as new anticancer agents …

The synthesis and antiplasmodial evaluation of new hybrids combining the pharmacophore
structures of artemisinin, ciprofloxacin or norfloxacin, and 7-chloroquinoline are reported in …

A principal factor that contributes towards the failure to eradicate leishmaniasis and
tuberculosis infections is the reduced efficacy of existing chemotherapies, owing to a …

The problems of parasite resistance, as well as the toxic residues to most of the
commercially available antipiroplasmic drugs severely weaken their effective, curative, and …

The study aimed to investigate the antibacterial activity, cytotoxicity, and mechanism of
action of the non-ionic, cyclic lipopeptide, serrawettin W2-FL10 against Staphylococcus …