[HTML][HTML] The immunomicrotope of Leishmania control and persistence

C Bogdan, D Barinberg, D Soulat, U Schleicher… - Trends in …, 2024 - cell.com
Leishmania is an intracellular protozoan transmitted by sand fly vectors; it causes
cutaneous, mucocutaneous, or visceral disease. Its growth and survival are impeded by type …

The intersection of host in vivo metabolism and immune responses to infection with kinetoplastid and apicomplexan parasites

S Ewald, A Nasuhidehnavi, TY Feng… - Microbiology and …, 2024 - Am Soc Microbiol
Protozoan parasite infection dramatically alters host metabolism, driven by immunological
demand and parasite manipulation strategies. Immunometabolic checkpoints are often …

Neutrophil-mediated hypoxia drives pathogenic CD8 T cell responses in cutaneous leishmaniasis

EA Fowler, CF Amorim, K Mostacada… - The Journal of …, 2024 - Am Soc Clin Investig
Cutaneous leishmaniasis caused by Leishmania parasites exhibits a wide range of clinical
manifestations. Although parasites influence disease severity, cytolytic CD8 T cell responses …

CCR5 promotes the migration of pathological CD8+ T cells to the leishmanial lesions

L Amorim Sacramento, C Farias Amorim… - Plos …, 2024 - journals.plos.org
Cytolytic CD8+ T cells mediate immunopathology in cutaneous leishmaniasis without
controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion …

Intratumoral microbiota as a novel prognostic indicator in bladder cancer

Y Zhang, H Lin, L Liang, S Jin, J Lv, Y Zhou, F Xu… - Scientific Reports, 2024 - nature.com
Microbes are important components of the tumor microenvironment and have a close
relationship with tumors. However, there is still a lack of research on the intratumoral …

Prokaryotic and eukaryotic skin microbiota modifications triggered by Leishmania infection in localized Cutaneous Leishmaniasis

J Jaimes, LH Patiño, G Herrera, C Cruz… - PLOS Neglected …, 2024 - journals.plos.org
Cutaneous Leishmaniasis (CL) is a tropical disease characterized by cutaneous ulcers,
sometimes with satellite lesions and nodular lymphangitis. Leishmania parasites …

[HTML][HTML] Investigation of parasite genetic variation and systemic immune responses in patients presenting with different clinical presentations of cutaneous …

E Yizengaw, Y Takele… - Infectious …, 2024 - idpjournal.biomedcentral.com
Cutaneous leishmaniasis (CL) is a neglected tropical skin disease, caused by the protozoan
parasite Leishmania. In Ethiopia, CL is mainly caused by Leishmania aethiopica and can …

Improved Treatment Outcome Following the Use of a Wound Dressings in Cutaneous Leishmaniasis Lesions

PB Borba, J Lago, T Lago, M Araújo-Pereira… - Pathogens, 2024 - mdpi.com
Leishmaniasis, caused by Leishmania parasites, is a neglected tropical disease and
Cutaneous Leishmaniasis (CL) is the most common form. Despite the associated toxicity …

Parasite genetic variation and systemic immune responses are not associated with different clinical presentations of cutaneous leishmaniasis caused by Leishmania …

E Yizengaw, Y Takele, SU Franssen, B Gashaw… - bioRxiv, 2024 - biorxiv.org
Cutaneous leishmaniasis (CL) is a neglected tropical skin disease, caused by the protozoan
parasite Leishmania (L.). It is endemic to 90 countries and causes> 200,000 new infections …