Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …

Cancer is the deadliest disease in the world behind heart disease. Sadly, this remains true
even as we suffer the ravages of the Covid-19 pandemic. Whilst current chemo-and …

CD47, overexpressed on kinds of tumor cells, activates a “don't eat me” signal through
binding to signal regulatory protein α (SIRPα), leading to immune escape from the …

Radiotherapy (RT), as one of the main methods in the clinical treatment of various malignant
tumors, would induce systemic immunotherapeutic effects by triggering immunogenic cell …

Anti-cancer drugs with various mechanisms emerge in succession, but most of free
therapeutics are accompanied by some disadvantages, such as poor safety and …

Immunogenic cell death (ICD) is a form of regulated cell death (RCD) induced by various
stresses and produces antitumor immunity via damage-associated molecular patterns …

Cancer is one of the top life‐threatening dangers to the human survival, accounting for over
10 million deaths per year. Bioactive glasses have developed dramatically since their …

The critical challenge for cancer vaccine‐induced T‐cell immunity is the sustained activation
of antigen cross‐presentation in antigen‐presenting cells (APCs) with innate immune …

The combination of immunogenic cell death (ICD) induction and immune checkpoint
blockade has emerged as a major direction of cancer immunotherapy. Among currently …

The low immunogenicity, insufficient infiltration of T lymphocytes, and dismal response to
immune checkpoint blockade therapy pose major difficulties in immunotherapy of pancreatic …