Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals
CA Legare, WM Raup-Konsavage, KE Vrana - Pharmacology, 2022 - karger.com
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …
Cannabidiol exerts anti-proliferative activity via a cannabinoid receptor 2-dependent mechanism in human colorectal cancer cells
HS Lee, G Tamia, HJ Song, D Amarakoon… - International …, 2022 - Elsevier
Colorectal cancer is the third leading cause of cancer incidence and mortality in the United
States. Cannabidiol (CBD), the second most abundant phytocannabinoid in Cannabis …
States. Cannabidiol (CBD), the second most abundant phytocannabinoid in Cannabis …
Secondary Terpenes in Cannabis sativa L.: Synthesis and Synergy
FT Chacon, WM Raup-Konsavage, KE Vrana… - Biomedicines, 2022 - mdpi.com
Cannabis is a complex biosynthetic plant, with a long history of medicinal use. While
cannabinoids have received the majority of the attention for their psychoactive and …
cannabinoids have received the majority of the attention for their psychoactive and …
Biological effects of cannabidiol on human cancer cells: Systematic review of the literature
C Valenti, M Billi, GL Pancrazi, E Calabria… - Pharmacological …, 2022 - Elsevier
This systematic review examine the biological effects of CBD, a major component of
therapeutic Cannabis, on human pathological and cancer cell populations of integumentary …
therapeutic Cannabis, on human pathological and cancer cell populations of integumentary …
Decoding the Postulated Entourage Effect of Medicinal Cannabis: What It Is and What It Isn't
C Christensen, M Rose, C Cornett, M Allesø - Biomedicines, 2023 - mdpi.com
The 'entourage effect'term was originally coined in a pre-clinical study observing
endogenous bio-inactive metabolites potentiating the activity of a bioactive …
endogenous bio-inactive metabolites potentiating the activity of a bioactive …
Analysis of anti-cancer and anti-inflammatory properties of 25 high-THC cannabis extracts
D Li, Y Ilnytskyy, E Ghasemi Gojani, O Kovalchuk… - Molecules, 2022 - mdpi.com
Cannabis sativa is one of the oldest cultivated plants. Many of the medicinal properties of
cannabis are known, although very few cannabis-based formulations became prescribed …
cannabis are known, although very few cannabis-based formulations became prescribed …
Cannabidiol and other phytocannabinoids as cancer therapeutics
G Nahler - Pharmaceutical Medicine, 2022 - Springer
Preclinical models provided ample evidence that cannabinoids are cytotoxic against cancer
cells. Among the best studied phytocannabinoids, cannabidiol (CBD) is most promising for …
cells. Among the best studied phytocannabinoids, cannabidiol (CBD) is most promising for …
Cannabinoids as potential Cancer therapeutics: the concentration conundrum
N Carkaci-Salli, WM Raup-Konsavage… - Cannabis and …, 2024 - liebertpub.com
Background: Studies have reported that cannabinoids, in particular Δ9-tetrahydrocannabinol
(Δ9-THC) and cannabidiol (CBD), significantly reduce cancer cell viability in vitro …
(Δ9-THC) and cannabidiol (CBD), significantly reduce cancer cell viability in vitro …
[HTML][HTML] The pharmacological effects of plant-derived versus synthetic cannabidiol in human cell lines
Introduction: Cannabidiol (CBD) can be isolated from Cannabis sativa L. or synthetically
produced. The aim of this study was to compare the in vitro effects of purified natural and …
produced. The aim of this study was to compare the in vitro effects of purified natural and …
Cannabinoids and endocannabinoid system changes in intestinal inflammation and colorectal cancer
V Cherkasova, O Kovalchuk, I Kovalchuk - Cancers, 2021 - mdpi.com
Simple Summary In recent years, multiple preclinical studies have shown that changes in
endocannabinoid system signaling may have various effects on intestinal inflammation and …
endocannabinoid system signaling may have various effects on intestinal inflammation and …