Acinetobacter baumannii phages: past, present and future

Q Tu, M Pu, Y Li, Y Wang, M Li, L Song, M Li, X An… - Viruses, 2023 - mdpi.com
Acinetobacter baumannii (A. baumannii) is one of the most common clinical pathogens and
a typical multi-drug resistant (MDR) bacterium. With the increase of drug-resistant A …

Bacteriophage tail proteins as a tool for bacterial pathogen recognition—a literature review

K Filik, B Szermer-Olearnik, S Oleksy, J Brykała… - Antibiotics, 2022 - mdpi.com
In recent years, a number of bacterial detection methods have been developed to replace
time-consuming culture methods. One interesting approach is to mobilize the ability of …

Specific Interaction of Novel Friunavirus Phages Encoding Tailspike Depolymerases with Corresponding Acinetobacter baumannii Capsular Types

AV Popova, MM Shneider, NP Arbatsky… - Journal of …, 2021 - Am Soc Microbiol
Acinetobacter baumannii is one of the most clinically important nosocomial pathogens. The
World Health Organization refers it to its “critical priority” category to develop new strategies …

Friunavirus Phage-Encoded Depolymerases Specific to Different Capsular Types of Acinetobacter baumannii

OY Timoshina, AA Kasimova, MM Shneider… - International Journal of …, 2023 - mdpi.com
Acinetobacter baumannii is a critical priority nosocomial pathogen that produces a variety of
capsular polysaccharides (CPSs), the primary receptors for specific depolymerase-carrying …

Mechanisms of Acinetobacter baumannii Capsular Polysaccharide Cleavage by Phage Depolymerases

YA Knirel, MM Shneider, AV Popova, AA Kasimova… - Biochemistry …, 2020 - Springer
Aerobic gram-negative bacterium Acinetobacter baumannii has recently become one of the
most relevant pathogens associated with hospital-acquired infections worldwide. A …

Isolation and Characterization of a Novel Myophage Abp9 Against Pandrug Resistant Acinetobacater baumannii

L Jiang, J Tan, Y Hao, Q Wang, X Yan… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii (A. baumannii) has emerged as one of the most troublesome
pathogens in health care institutions. A. baumannii can cause a wide range of diseases in …

Identification of a Novel Acinetobacter baumannii Phage-Derived Depolymerase and Its Therapeutic Application in Mice

C Wang, P Li, Y Zhu, Y Huang, M Gao, X Yuan… - Frontiers in …, 2020 - frontiersin.org
The rapid expansion of Acinetobacter baumannii clinical isolates exhibiting resistance to
most or all available antibiotics is a global concern. Current treatments for infections caused …

A novel tail-associated O91-specific polysaccharide depolymerase from a podophage reveals lytic efficacy of Shiga toxin-producing Escherichia coli

Y Chen, X Li, S Wang, L Guan, X Li, D Hu… - Applied and …, 2020 - Am Soc Microbiol
Shiga toxin-producing Escherichia coli (STEC) strains are important zoonotic foodborne
pathogens, causing diarrhea, hemorrhagic colitis, and life-threatening hemolytic uremic …

Antibacterial activity of vB_AbaM_PhT2 phage hydrophobic amino acid fusion endolysin, combined with colistin against Acinetobacter baumannii

S Sitthisak, S Manrueang, S Khongfak… - Scientific Reports, 2023 - nature.com
Phage lytic enzymes are promising antimicrobial agents. In this study, an endolysin derived
from vB_AbaM_PhT2 (vPhT2), was identified. This endolysin represented the conserved …

The Acinetobacter baumannii K70 and K9 capsular polysaccharides consist of related K-units linked by the same Wzy polymerase and cleaved by the same phage …

AA Kasimova, NS Sharar, SJ Ambrose… - Microbiology …, 2023 - Am Soc Microbiol
The extensively antibiotic-resistant Acinetobacter baumannii GC1 (ST1IP) isolate SGH0807
from Singapore carries the KL70 gene cluster. The structure of the K70 capsular …