Understanding of the biological basis for susceptibility to malaria in pregnancy was recently
advanced by the discovery that erythrocytes infected with Plasmodium falciparum …

Glycosaminoglycans (GAGs) are complex linear polysaccharides expressed in intracellular
compartments, at the cell surface, and in the extracellular environment where they interact …

Background. Molecular, as opposed to microscopic, detection measures the real prevalence
of Plasmodium falciparum infections. Such occult infections are common during pregnancy …

Pregnant women are susceptible to malaria during pregnancy. Plasmodium falciparum,
which sequesters in the placenta, causes the greatest disease, contributing significantly to …

For more than one hundred years, several treatments against malaria have been proposed
but they have systematically failed, mainly due to the occurrence of drug resistance in part …

Apicomplexans are a group of pathogenic protists that cause various diseases in humans
and animals that cause economic losses worldwide. These unicellular eukaryotes are …

Placental malaria is caused by Plasmodium falciparum–infected erythrocytes that bind to
placental tissue. Binding is mediated by VAR2CSA, a parasite antigen coded by the var …

During placental malaria, Plasmodium falciparum infected erythrocytes sequester in the
placenta, causing health problems for both the mother and fetus. The specific adherence is …

Many microbial pathogens subvert proteoglycans for their adhesion to host tissues, invasion
of host cells, infection of neighbouring cells, dissemination into the systemic circulation, and …

Background Malaria infection during pregnancy can result in placental malaria and is
associated with adverse pregnancy outcomes particularly among primigravidae. The aim of …