Reactive oxygen species (ROS) are reactive intermediates of molecular oxygen that act as
important second messengers within the cells; however, an imbalance between generation …

Abstract Peroxiredoxin 6 (Prdx6) is the prototype and the only mammalian 1-Cys member of
the Prdx family. Major differences from 2-Cys Prdxs include the use of glutathione (GSH) …

Peroxiredoxin 6 represents a widely distributed group of peroxiredoxins that contain a single
conserved cysteine in the protein monomer (1-cys Prdx). The cys when oxidized to the …

Reactive oxygen species (ROS) can be both beneficial and deleterious. Under normal
physiological conditions, ROS production is tightly regulated, and ROS participate in both …

1-cys peroxiredoxin (1-cysPrx), a member of the peroxiredoxin superfamily, can protect cells
against membrane oxidation through glutathione (GSH)-dependent reduction of …

Peroxiredoxin 6 (Prdx6), a bifunctional 25-kDa protein with both GSH peroxidase and
phospholipase A2 activities, is the only mammalian 1-Cys member of the peroxiredoxin …

Reactive oxygen species, especially hydrogen peroxide, are important in cellular signal
transduction. However, excessive amounts of these species damage tissues and cells by …

Although lipid peroxidation associated with oxidative stress can result in cellular death, sub-
lethal lipid peroxidation can gradually resolve with return to the pre-exposure state. We have …

Cigarette smoke, the major risk factor for lung cancer, induces an accumulation of reactive
oxygen species. These have multiple effects on cell defense, cell proliferation and cell …

The aim of the study was to investigate the protective effect of dioscin against APAP-induced
hepatotoxicity. In the in vitro tests, HepG2 cells were given APAP pretreatment with or …