Transposable elements (TEs) are major components of eukaryotic genomes. However, the
extent of their impact on genome evolution, function, and disease remain a matter of intense …

The ultimate form of parasitism and evasion of host immunity is for the parasite genome to
enter the germ line of the host species. Retroviruses have invaded the host germ line on the …

Endogenous retroviruses (ERVs) have contributed to more than 8% of the human genome.
The majority of these elements lack function due to accumulated mutations or internal …

Human endogenous retroviruses (HERVs) represent 8% of the human genome. HERV
products may represent tumor antigens relevant for cancer immunotherapy. We developed a …

Cancer arises from a series of genetic and epigenetic changes, which result in abnormal
expression or mutational activation of oncogenes, as well as suppression/inactivation of …

Like all other mammals, humans harbour an astonishing number of endogenous
retroviruses (ERVs), as well as other retroelements, embedded in their genome. These …

The male genital tract (MGT) is the target of a number of viral infections that can have
deleterious consequences at the individual, offspring, and population levels. These …

Human endogenous retroviruses (HERVs) comprise nearly 8% of the human genome and
are derived from ancient integrations of retroviruses into the germline. The biology of HERVs …

Transposable elements, including endogenous retroviruses (ERVs), comprise almost 45%
of the human genome. This could represent a significant pathogenic burden but it is …

In contrast to other cancer types, melanoma incidence has been increasing over the last 50
years, and while it still represents less than 5% of all cutaneous malignancies, melanoma …