Muscle fatigue is an exercise-induced reduction in maximal voluntary muscle force. It may
arise not only because of peripheral changes at the level of the muscle, but also because …

Much is known about the physiological impairments that can cause muscle fatigue. It is
known that fatigue can be caused by many different mechanisms, ranging from the …

1. Voluntary activation of elbow flexor muscles can be optimal during brief maximal voluntary
contractions (MVCs), although central fatigue, a progressive decline in the ability to drive the …

We investigated the reproducibility of measurements of maximal voluntary torque and
maximal voluntary activation using twitch interpolation. On 5 days, each of 5 subjects …

The purpose of this study was to estimate the relative contributions of central and peripheral
factors to the development of human muscle fatigue. Nine healthy subjects [five male, four …

The manifestations of fatigue, as observed by reductions in the ability to produce a given
force or power, are readily apparent soon after the initiation of intense activity. Moreover …

Skeletal Muscle: Form and Function, Second Edition, provides readers with a detailed
understanding of the different facets of muscle physiology. Meticulously researched and …

The twitch interpolation technique is commonly employed to assess the completeness of
skeletal muscle activation during voluntary contractions. Early applications of twitch …

Muscle fatigue or neuromuscular disease may result in central activation failure during
maximal voluntary contractions (MVCs). Superimposition of an electrically stimulated …

Because patients who fail a trial of weaning from mechanical ventilation experience a
marked increase in respiratory load, we hypothesized that these patients develop …