This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

Various forms of self-loss have been described as aspects of mental illness (eg,
depersonalization disorder), but might self-loss also be related to mental health? In this …

Recent clinical trials show that psychedelics such as LSD and psilocybin can be given safely
in controlled conditions, and can cause lasting psychological benefits with one or two …

Naturally occurring and psychedelic drug–occasioned experiences interpreted as personal
encounters with God are well described but have not been systematically compared. In this …

The psychological mechanisms of action involved in psilocybin-assisted psychotherapy are
not yet well understood. Despite a resurgence of quantitative research regarding psilocybin …

The concept of transformative experience (TE) has been widely explored by several
disciplines from philosophy to neurobiology, and in different domains, from the spiritual to …

The acute subjective effects of psychedelics are responsive to users' expectations and
surroundings (ie,“set and setting”). Accordingly, a great deal of thought has gone into …

Awe is a complex emotion arising from the perception of literal or figurative vastness.
Several subjective components of awe have been identified, including feelings of …

A psychological model of classic psychedelic-assisted psychotherapy informed by
contemporary scientific data is presented in this paper. It is suggested that classic …

Meditation and psychedelics have played key roles in humankind's search for self-
transcendence and personal change. However, neither their possible synergistic effects, nor …