Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022 - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

[HTML][HTML] Silica nanoparticles: Biomedical applications and toxicity

Y Huang, P Li, R Zhao, L Zhao, J Liu, S Peng… - Biomedicine & …, 2022 - Elsevier
Silica nanoparticles (SiNPs) are composed of silicon dioxide, the most abundant compound
on Earth, and are used widely in many applications including the food industry, synthetic …

[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers

TI Janjua, Y Cao, F Kleitz, M Linden, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …

Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier & targeting ligand

AO Elzoghby, MA Abdelmoneem, IA Hassanin… - Biomaterials, 2020 - Elsevier
Recent progress in protein-based nanomedicine, inspired by the success of Abraxane®
albumin-paclitaxel nanoparticles, have resulted in novel therapeutics used for treatment of …

Blood-brain delivery methods using nanotechnology

DM Teleanu, C Chircov, AM Grumezescu, A Volceanov… - Pharmaceutics, 2018 - mdpi.com
Pathologies of the brain, of which brain cancer, Alzheimer's disease, Parkinson's disease,
stroke, and multiple sclerosis, are some of the most prevalent, and that presently are poorly …

Functionalized nanomaterials capable of crossing the blood–brain barrier

S Zha, H Liu, H Li, H Li, KL Wong, AH All - ACS nano, 2024 - ACS Publications
The blood–brain barrier (BBB) is a specialized semipermeable structure that highly
regulates exchanges between the central nervous system parenchyma and blood vessels …

Advances in receptor‐mediated, tumor‐targeted drug delivery

DE Large, JR Soucy, J Hebert… - Advanced …, 2019 - Wiley Online Library
Receptor‐mediated drug delivery presents an opportunity to enhance therapeutic efficiency
by accumulating drug within the tissue of interest and reducing undesired, off‐target effects …

Dye-doped silica nanoparticles: synthesis, surface chemistry and bioapplications

V Gubala, G Giovannini, F Kunc, MP Monopoli… - Cancer …, 2020 - Springer
Background Fluorescent silica nanoparticles have been extensively utilised in a broad
range of biological applications and are facilitated by their predictable, well-understood …

Protein-based nanomaterials and nanosystems for biomedical applications: A review

S Ding, N Zhang, Z Lyu, W Zhu, YC Chang, X Hu, D Du… - Materials Today, 2021 - Elsevier
Advanced protein-based nanomaterials and nanosystems (PNNS) have attracted
considerable scientific interest in recent decades due to their potential in bio-applications …

[HTML][HTML] Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma

TI Janjua, Y Cao, A Ahmed-Cox, A Raza… - Journal of Controlled …, 2023 - Elsevier
The prognosis of brain cancers such as glioblastoma remains poor despite numerous
advancements in the field of neuro-oncology. The presence of the blood brain barrier (BBB) …