Peroxisome proliferator-activated receptor (PPAR) α, β/δ, and γ modulate lipid homeostasis.
PPARα regulates lipid metabolism in the liver, the organ that largely controls whole-body …

Oxidative stress is a reflection of the imbalance between the production of reactive oxygen
species (ROS) and the scavenging capacity of the antioxidant system. Excessive ROS …

Ligand-activated nuclear receptors, including peroxisome proliferator-activated receptor
alpha (PPARα), pregnane X receptor, and constitutive androstane receptor, were first …

Colorectal cancer (CRC) is one of the most commonly diagnosed cancers, and it is
characterized by genetic and epigenetic alterations, as well as by inflammatory cell …

Non-alcoholic fatty liver disease (NAFLD) is a major chronic liver disease that can lead to
liver cirrhosis, liver cancer, and ultimately death. NAFLD is pathologically classified as non …

Aronia melanocarpa berries (chokeberries) constitute a very rich source of numerous
substances exerting a beneficial impact on health, including mainly polyphenols …

With slowly increasing survival rates in pancreatic cancer and international consensus
guidelines recommending surgical resection of premalignant lesions, survival post …

Background Nonalcoholic fatty liver disease (NAFLD) has become the most common form of
chronic liver disease in both adults and children worldwide. Understanding the pathogenic …

AIM To assess whether surrogate biomarkers of endotoxemia were correlated with the
histological features of nonalcoholic fatty liver disease (NAFLD). METHODS One hundred …

Limited information exists on the impact of flavonoid intake on nonalcoholic fatty liver
disease (NAFLD). We evaluated the link between flavonoid intake, liver tests and risk of …