Single-molecule protein sensing in a nanopore: a tutorial

N Varongchayakul, J Song, A Meller… - Chemical Society …, 2018 - pubs.rsc.org
Proteins are the structural elements and machinery of cells responsible for a functioning
biological architecture and homeostasis. Advances in nanotechnology are catalyzing key …

Overview of the materials design and sensing strategies of nanopore devices

L Liang, F Qin, S Wang, J Wu, R Li, Z Wang… - Coordination Chemistry …, 2023 - Elsevier
Nanopore platform holds a great fascination that attracts increasing interests in research and
leads the development of various domains. Herein we first briefly introduce the …

Protein identification by nanopore peptide profiling

FLR Lucas, RCA Versloot, L Yakovlieva… - Nature …, 2021 - nature.com
Nanopores are single-molecule sensors used in nucleic acid analysis, whereas their
applicability towards full protein identification has yet to be demonstrated. Here, we show …

Electrochemical sensing at a confined space

SM Lu, YY Peng, YL Ying, YT Long - Analytical chemistry, 2020 - ACS Publications
Single entity sensing is recently an area of tremendous interest in analytical chemistry, such
that it is possible to analyze single cells, single particles, and even single molecules. Among …

Bio-inspired track-etched polymeric nanochannels: steady-state biosensors for detection of analytes

J Wang, Y Zhou, L Jiang - ACS nano, 2021 - ACS Publications
Bio-inspired polymeric nanochannel (also referred as nanopore)-based biosensors have
attracted considerable attention on account of their controllable channel size and shape …

Supramolecular framework membrane for precise sieving of small molecules, nanoparticles and proteins

G Zhang, X Li, G Chen, Y Zhang, M Wei, X Chen… - Nature …, 2023 - nature.com
Synthetic framework materials have been cherished as appealing candidates for separation
membranes in daily life and industry, while the challenges still remain in precise control of …

A reversibly gated protein-transporting membrane channel made of DNA

S Dey, A Dorey, L Abraham, Y Xing, I Zhang… - Nature …, 2022 - nature.com
Controlled transport of biomolecules across lipid bilayer membranes is of profound
significance in biological processes. In cells, cargo exchange is mediated by dedicated …

Detection of Unfolded Cellular Proteins Using Nanochannel Arrays with Probe‐Functionalized Outer Surfaces

Y Qiao, JJ Hu, Y Hu, C Duan, W Jiang… - Angewandte Chemie …, 2023 - Wiley Online Library
Nanochannel technology has emerged as a powerful tool for label‐free and highly sensitive
detection of protein folding/unfolding status. However, utilizing the inner walls of a …

Revisiting the origin of nanopore current blockage for volume difference sensing at the atomic level

MY Li, YL Ying, J Yu, SC Liu, YQ Wang, S Li, YT Long - Jacs Au, 2021 - ACS Publications
Changes in the nanopore ionic current during entry of a target molecule underlie the
sensing capability and dominate the intensity and extent of applications of the nanopore …

Fabrication and practical applications of molybdenum disulfide nanopores

M Graf, M Lihter, M Thakur, V Georgiou, J Topolancik… - Nature protocols, 2019 - nature.com
Among the different developed solid-state nanopores, nanopores constructed in a
monolayer of molybdenum disulfide (MoS2) stand out as powerful devices for single …