Comparison of allogeneic stem cell transplant and autologous stem cell transplant in refractory or relapsed peripheral T-cell lymphoma: a systematic review and meta …

J Du, D Yu, X Han, L Zhu, Z Huang - JAMA Network Open, 2021 - jamanetwork.com
Importance Hematopoietic stem cell transplant (HSCT) is an advisable option for refractory
or relapsed peripheral T-cell lymphoma (R/R-PTCL), but whether allogeneic HSCT or …

[HTML][HTML] PTCL, NOS: An update on classification, risk-stratification, and treatment

J Weiss, J Reneau, RA Wilcox - Frontiers in Oncology, 2023 - frontiersin.org
The peripheral T-cell lymphomas (PTCL) are relatively rare, heterogeneous, and
therapeutically challenging. While significant therapeutic gains and improved understanding …

Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma

M Vanden Bempt, K Debackere… - Blood, The Journal …, 2022 - ashpublications.org
Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of hematological cancers
arising from the malignant transformation of mature T cells. In a cohort of 28 PTCL cases, we …

Peripheral T‐cell lymphoma with a T follicular‐helper phenotype: A different entity? Results of the Spanish Real‐T study

A Martín García‐Sancho… - British Journal of …, 2023 - Wiley Online Library
Nodal peripheral T‐cell lymphoma (PTCL) with a T follicular helper phenotype (PTCL‐TFH)
is a new type of PTCL. We aimed to define its clinical characteristics and prognosis …

[HTML][HTML] Allogeneic blood or marrow transplantation with post-transplantation cyclophosphamide for peripheral T cell lymphoma: the importance of graft source

CH Sterling, MS Hughes, HL Tsai, K Yarkony… - … and cellular therapy, 2023 - Elsevier
The use of post-transplantation cyclophosphamide (PTCy) for graft-versus host-disease
(GVHD) prophylaxis has revolutionized allogeneic blood or marrow transplantation …

[HTML][HTML] Precise diagnosis and targeted therapy of nodal T-follicular helper cell lymphoma (T-FHCL)

J Du, S Jin, M Zhang, X Fu, J Yang, L Zhang… - Frontiers in …, 2023 - frontiersin.org
Nodal T-follicular helper cell lymphoma (T-FHCL) derived from T-follicular helper (Tfh) cell
falls into a heterogeneous category of peripheral T-cell lymphoma (PTCL). Due to the limited …

Enhancer of Zeste Homolog 2 Inhibitor SHR2554 in Relapsed or Refractory Peripheral T-cell Lymphoma: Data from the First-in-Human Phase I Study

Y Song, Z Jin, ZM Li, Y Liu, L Li, C He, H Su… - Clinical Cancer …, 2024 - AACR
Purpose: Patients with peripheral T-cell lymphomas (PTCL) in the relapsed or refractory (r/r)
setting have only a limited number of therapies available, and the prognosis is extremely …

[HTML][HTML] Circulating Tumor DNA–Based Genotyping and Monitoring for Predicting Disease Relapses of Patients with Peripheral T-Cell Lymphomas

SJ Kim, YJ Kim, SE Yoon, KJ Ryu, B Park… - Cancer Research and …, 2023 - ncbi.nlm.nih.gov
Purpose Plasma circulating tumor DNA (ctDNA) could reflect the genetic alterations present
in tumor tissues. However, there is little information about the clinical relevance of cell-free …

SOHO state of the art updates and next questions| new pathways and new targets in PTCL: staying on target

SA Carty, CA Murga-Zamalloa, RA Wilcox - Clinical Lymphoma Myeloma …, 2023 - Elsevier
While the peripheral T-cell lymphomas (PTCL) remain a therapeutic challenge, and
increasingly account for a disproportionate number of lymphoma-related deaths, improved …

[HTML][HTML] Efficacy and treatment-related adverse events of romidepsin in PTCL clinical studies: a systematic review and meta-analysis

J Du, X Han, S Lin, C Qiu, L Zhu, Z Huang… - Frontiers in Medicine, 2021 - frontiersin.org
Background: Peripheral T-cell lymphoma (PTCL) is an extensive class of biologically and
clinically heterogeneous diseases with dismal outcomes. The histone deacetylase inhibitor …