[HTML][HTML] Irritable bowel syndrome: pathogenesis, diagnosis, treatment, and evidence-based medicine

L Saha - World Journal of Gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is a chronic and debilitating functional gastrointestinal
disorder that affects 9%-23% of the population across the world. The percentage of patients …

Fiber and functional gastrointestinal disorders

S Eswaran, J Muir, WD Chey - … journal of the American College of …, 2013 - journals.lww.com
Despite years of advising patients to alter their dietary and supplementary fiber intake, the
evidence surrounding the use of fiber for functional bowel disease is limited. This paper …

A primer on effectiveness and efficacy trials

AG Singal, PDR Higgins, AK Waljee - Clinical and translational …, 2014 - journals.lww.com
Although efficacy and effectiveness studies are both important when evaluating
interventions, they serve distinct purposes and have different study designs. Unfortunately …

Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles

L O'Mahony, J McCarthy, P Kelly, G Hurley, F Luo… - Gastroenterology, 2005 - Elsevier
Background&Aims: The aim of this study was to compare the response of symptoms and
cytokine ratios in irritable bowel syndrome (IBS) with ingestion of probiotic preparations …

AGA technical review on irritable bowel syndrome

DA Drossman, M Camilleri, EA Mayer, WE Whitehead - Gastroenterology, 2002 - Elsevier
The irritable bowel syndrome (IBS) is part of the larger group of functional gastrointestinal
(GI) disorders that, despite differences in location and symptom patterns, share common …

Management of functional somatic syndromes

P Henningsen, S Zipfel, W Herzog - The Lancet, 2007 - thelancet.com
Although functional somatic syndromes (FSS) show substantial overlap, treatment research
is mostly confined to single syndromes, with a lack of valid and generally accepted …

[HTML][HTML] Irritable bowel syndrome: a clinical review

RLS Soares - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) remains a clinical challenge in the 21 st century. It's the most
commonly diagnosed gastrointestinal condition and also the most common reason for …

[HTML][HTML] The role of visceral hypersensitivity in irritable bowel syndrome: pharmacological targets and novel treatments

MH Farzaei, R Bahramsoltani, M Abdollahi… - Journal of …, 2016 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is the most common disorder referred to gastroenterologists
and is characterized by altered bowel habits, abdominal pain, and bloating. Visceral …

Dietary triggers of abdominal symptoms in patients with irritable bowel syndrome: randomized placebo-controlled evidence

SJ Shepherd, FC Parker, JG Muir, PR Gibson - Clinical gastroenterology …, 2008 - Elsevier
Background & Aims: Observational studies suggest dietary fructose restriction might lead to
sustained symptomatic response in patients with irritable bowel syndrome (IBS) and fructose …

Bulking agents, antispasmodics and antidepressants for the treatment of irritable bowel syndrome

L Ruepert, AO Quartero, NJ de Wit… - Cochrane database …, 2011 - cochranelibrary.com
Background Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disorder.
The role of pharmacotherapy for IBS is limited and focused mainly on symptom control …