Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Endothelial cells are important constituents of blood vessels that play critical roles in
cardiovascular homeostasis by regulating blood fluidity and fibrinolysis, vascular tone …

Actions of symbiotic gut microbiota are in dynamic balance with the host's organism to
maintain homeostasis. Many different factors have an impact on this relationship, including …

Hydrogen sulfide (H2S) is a ubiquitous signaling molecule with important functions in many
mammalian organs and systems. Observations in the 1990s ascribed physiological actions …

Hydrogen sulfide (H2S) has arisen as a critical gasotransmitter signaling molecule
modulating cellular biological events related to health and diseases in heart, brain, liver …

Background The vascular endothelium represents a fundamental mechanical and biological
barrier for the maintenance of vascular homeostasis along the entire vascular tree. Changes …

Endothelial dysfunction (EDF) reflects pathophysiological changes in the phenotype and
functions of endothelial cells that result from and/or contribute to a plethora of cardiovascular …

Nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S) are three
endogenously produced gases with important functions in the vasculature, immune defense …

Abstract Significance: Hydrogen sulfide (H2S) has only recently gained recognition for its
physiological effects. It is synthesized widely in the mammalian tissues and regulates …

Background: Hydrogen sulfide (H2S) has antihypertension and anti-inflammatory effects,
and its endogenous-generation key enzyme cystathionine γ lyase (CSE) is expressed in …