Background AS1411 is a 26-mer G-rich DNA oligonucleotide that forms a variety of G-
quadruplex structures. It was identified based on its cancer-selective antiproliferative activity …

The non-structural (NS1) protein of influenza A viruses is a non-essential virulence factor
that has multiple accessory functions during viral infection. In recent years, the major role …

The nucleolus is a sub-nuclear body known primarily for its role in ribosome biogenesis.
Increased number and/or size of nucleoli have historically been used by pathologists as a …

Most viruses express one or several proteins that counter the antiviral defences of the host
cell. This is the task of non-structural protein NS1 in influenza viruses. Absent in the viral …

Hepatitis B virus (HBV) remains a major public health threat with nearly 300 million people
chronically infected worldwide who are at a high risk of developing hepatocellular …

Viruses are small obligatory parasites and as a consequence, they have developed
sophisticated strategies to exploit the host cell's functions to create an environment that …

Fluorogenic hybridization probes that allow RNA imaging provide information as to how the
synthesis and transport of particular RNA molecules is orchestrated in living cells. In this …

Abstract Nonstructural protein 1 (NS1) of influenza A virus plays a central role in virus
replication and blockade of the host innate immune response, and is therefore being …

PA-X, a fusion protein belonging to influenza A viruses (IAVs), integrating the N-terminal 191
amino acids of PA gene and the ribosomal frame-shifting product that lengthens out to 41 or …

Viruses are intracellular pathogens that have to usurp some of the cellular machineries to
provide an optimal environment for their own replication. An increasing number of reports …